In this episode we discuss:

The major issues with the ROS theory of obesity


Why fat-burning is inefficient and doesn’t lead to healthy fat loss


The real problem with PUFA (and why they don’t decrease ROS production)


Why carbohydrates and insulin don’t cause fat gain

How increasing cellular energy through efficient mitochondrial respiration is the key to healthy fat loss

 
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Click here to check out the show notes: https://jayfeldmanwellness.com/ep-47-a-critique-of-the-ros-theory-of-obesity-the-croissant-diet-part-1/

 
Timestamps:
3:26 – an introduction to The Croissant Diet and Fire In A Bottle
10:04 – an introduction to ROS and the varying ROS-producing effects of fats and carbs

16:10 – the ROS theory of obesity, Randle cycle confusion, and how fat-burning causes physiological insulin resistance
25:30 – the effect of fatty acid saturation on ROS production when oxidized in mitochondria
29:36 – the real problem with PUFA and why they lead to increases in ROS production rather than decreases
42:28 – why the inefficient mitochondrial respiration that’s fueled by fatty acid oxidation and produces excessive amounts of ROS harms our health
47:39 – the problems with the idea of hormesis
58:39 – why fat-burning doesn’t increase fat loss
1:05:45 – anti-hormesis and the bioenergetic view of obesity