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Choline Deficiency: One Reason (Of Many) to Avoid a Vegan Diet
Choline Deficiency: One Reason (Of Many) to Avoid a Vegan Diet
ratings:
Length:
7 minutes
Released:
Sep 3, 2019
Format:
Podcast episode
Description
Going vegan is all the rage today. Along with the belief it will save the planet, some believe it's also a healthier way to eat.
I expect the vegan diet will get even more popular this fall when Arnold Schwarzenegger and James Cameron release their movie The Game Changers. I mean, if most of Hollywood is behind a movement or agenda, it must be the right way to go, right (insert sarcasm here)?
As you might imagine, I'm not a proponent of a vegan diet.
In addition to the more obvious issues of, like missing out on the benefits of a higher-protein diet and omega-3 fats, a just-published article in the British Medical Journal points out another significant concern: choline deficiency.
What is Choline?
Choline is one of many micronutrients found in animal-based foods. Your body can’t make enough of it, and you don't get much from plant-based foods.
[Choline] is needed for neurotransmitter synthesis (acetylcholine), cell-membrane signaling (phospholipids), lipid transport (lipoproteins), and methyl-group metabolism (homocysteine reduction).
Zeisel and de Costa
Pregnant women who follow a vegan diet are at the greatest risk of choline deficiency. Choline needs double during pregnancy, and inadequate intakes can cause significant damage to the developing baby.
After birth, babies need high levels of choline too. Human breast milk is rich in it. Though a mother's choline production increases during pregnancy, the massive amount delivered to the fetus, and then to the baby through breast milk, can quickly deplete the mother’s stores of the nutrient.
In addition to causing cognitive dysfunction in infants, choline deficiency in older adults leads to other problems like fatty liver and muscle damage.
In fact, research shows people have developed liver damage when deficient in choline, even when they supplemented with other important micronutrients like methionine and folate.
A high-quality multivitamin should include choline, but that doesn't mean you can use a quality multi and skip out on animal products and meet your needs. You need both.
Health Risks of Choline Deficiency
The following are some health risks of insufficient choline intake.
Increased risk of neural tube defects
Though increasing folate consumption helps to reduce the risk of neural tube defects, adequate choline is also needed.
In one study, women in the lowest quartile for choline intake had a four times higher risk of delivering babies with neural tube defect compared to the women in the highest quartile.
Compromised Memory and Cognitive Function
Animal research shows that choline deficiency can compromise memory development in a developing fetus. Interestingly, animal research also shows that if a mother consumes extra choline during pregnancy, it may reduce memory loss in old age of the mother’s offspring.
More simply, a mother’s choline consumption could reduce the chance that her son or daughter will develop memory loss when they get old.
Low choline intakes can lead to other neurological problems as well.
Increased Risk of Cardiovascular Disease
Elevated homocysteine is a risk factor for heart disease. To lower homocysteine levels, it must be methylated. However, low choline levels compromise the methylation process and increase the risk of heart disease. Elevated homocysteine may also contribute to cancer, cognitive decline and bone fractures.
Those with higher choline and betaine intakes have lower levels of inflammation, which can also affect cardiovascular disease risk.
Increased Cancer Risk
Low choline levels contribute to DNA damage and cell death. Research has shown a clear connection between low choline intakes and breast cancer risk. However, some research also shows lymphocytes can be damaged by low choline levels, which could contribute to other forms of cancer.
Increased Risk of Fatty Liver Disease
I already mentioned the fact that choline is necessary for methy...
I expect the vegan diet will get even more popular this fall when Arnold Schwarzenegger and James Cameron release their movie The Game Changers. I mean, if most of Hollywood is behind a movement or agenda, it must be the right way to go, right (insert sarcasm here)?
As you might imagine, I'm not a proponent of a vegan diet.
In addition to the more obvious issues of, like missing out on the benefits of a higher-protein diet and omega-3 fats, a just-published article in the British Medical Journal points out another significant concern: choline deficiency.
What is Choline?
Choline is one of many micronutrients found in animal-based foods. Your body can’t make enough of it, and you don't get much from plant-based foods.
[Choline] is needed for neurotransmitter synthesis (acetylcholine), cell-membrane signaling (phospholipids), lipid transport (lipoproteins), and methyl-group metabolism (homocysteine reduction).
Zeisel and de Costa
Pregnant women who follow a vegan diet are at the greatest risk of choline deficiency. Choline needs double during pregnancy, and inadequate intakes can cause significant damage to the developing baby.
After birth, babies need high levels of choline too. Human breast milk is rich in it. Though a mother's choline production increases during pregnancy, the massive amount delivered to the fetus, and then to the baby through breast milk, can quickly deplete the mother’s stores of the nutrient.
In addition to causing cognitive dysfunction in infants, choline deficiency in older adults leads to other problems like fatty liver and muscle damage.
In fact, research shows people have developed liver damage when deficient in choline, even when they supplemented with other important micronutrients like methionine and folate.
A high-quality multivitamin should include choline, but that doesn't mean you can use a quality multi and skip out on animal products and meet your needs. You need both.
Health Risks of Choline Deficiency
The following are some health risks of insufficient choline intake.
Increased risk of neural tube defects
Though increasing folate consumption helps to reduce the risk of neural tube defects, adequate choline is also needed.
In one study, women in the lowest quartile for choline intake had a four times higher risk of delivering babies with neural tube defect compared to the women in the highest quartile.
Compromised Memory and Cognitive Function
Animal research shows that choline deficiency can compromise memory development in a developing fetus. Interestingly, animal research also shows that if a mother consumes extra choline during pregnancy, it may reduce memory loss in old age of the mother’s offspring.
More simply, a mother’s choline consumption could reduce the chance that her son or daughter will develop memory loss when they get old.
Low choline intakes can lead to other neurological problems as well.
Increased Risk of Cardiovascular Disease
Elevated homocysteine is a risk factor for heart disease. To lower homocysteine levels, it must be methylated. However, low choline levels compromise the methylation process and increase the risk of heart disease. Elevated homocysteine may also contribute to cancer, cognitive decline and bone fractures.
Those with higher choline and betaine intakes have lower levels of inflammation, which can also affect cardiovascular disease risk.
Increased Cancer Risk
Low choline levels contribute to DNA damage and cell death. Research has shown a clear connection between low choline intakes and breast cancer risk. However, some research also shows lymphocytes can be damaged by low choline levels, which could contribute to other forms of cancer.
Increased Risk of Fatty Liver Disease
I already mentioned the fact that choline is necessary for methy...
Released:
Sep 3, 2019
Format:
Podcast episode
Titles in the series (100)
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