In this episode, I share how you can have the biggest chance of success in your fat-loss endeavours & explain the importance of considering the magnitude of effect in your strategies. I also reveal a few details about the upcoming Mac-Nutrition event MNU LIVE and why you need to be there this year!  References for the studies discussed can be found at www.Martin-MacDonald.com/EP49 TOPICS 00:27 - The science of losing fat in a specific area - aka Spot Reduction 04:43 - What not to do if you want smaller legs 11:16 - What is the ‘be all and end all’ of fat loss? 12:48 - PCOS, Carbs and calories: An adherence case study 18:17 - Targeted strategies for any goal work best 22:14 - Adherence must be specific but it is the most important factor