In this guest episode, Leonard Calabrese, DO, provides the history of systemic lupus erythematosus, with special emphasis on the discovery of the LE cell and the two clinics involved in its detection.   Introduction of Leonard Calabrese, DO :11 In this episode … 1:44 A brief history of systemic lupus erythematosus and the major players 2:15 Laurent-Theodore Biett 2:55 Casanave 3:05 von Hebra 3:24 Moritz Kaposi 4:05 Sir William Osler 5:25 Fast-forward to observations made during WWII era 7:00 The story of two clinics 8:55 The Mayo Clinic 9:00 The Cleveland Clinic 16:24 A race against time 18:29 Lupus is no longer a diagnostic problem 20:02 In a nutshell 20:15 Housekeeping items 20:51 Leonard Calabrese, DO, is head of Cleveland Clinic’s Section of Clinical Immunology, co-director of Center for Vasculitis Care and Research, and chief medical editor of Healio Rheumatology. We’d love to hear from you! Send your comments/questions to rheuminationspodcast@healio.com. Follow us on Twitter @AdamJBrownMD @HealioRheum @HRheuminations @LCalabreseDO