What is silica? How does it impact your risk of developing autoimmunity if you inhale it, inject it or even snort it up your nose? Listen and find out! ·       Intro 0:12 ·       In the previous episodes 0:28 ·       The Ajax incident of 1979 1:15 ·       Silica and its association with autoimmune disease 4:11 ·       The history of silica and the health risks 5:21 ·       Rheumatoid scleroderma, etc. 8:14 ·       Cardiff pneumoconiosis medical panel 9:49 ·       Databases 12:51 ·       Silica exposure and the development of serologies 15:02 ·       What would happen if you injected silica into the veins? 16:51 ·       Anca vasculitis 18:33 ·       Thanks for listening 23:23 Disclosures: Brown reports no relevant financial disclosures. We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Blanc PD, et al. Am J Med. 2015;doi:10.1016/j.amjmed.2015.05.001. Boudigaard SH, et al. Int J Epidemiol. 2021;doi:10.1093/ije/dyaa287. Conrad K, et al. Lupus. 1996;doi:10.1177/096120339600500112. Hoy RF, et al. Allergy. 2020;doi:10.111/all.14202. Klockars M, et al. Br Med J (Clin Res Ed). 1987;doi:10.1136/bmj.294.6578.997. Park CG, et al. Environ Health Perspect. 1999;doi:10.1289/ehp.99107s5793. Pollard KM. Front Immunol. 2016;doi:10.3389/fimmu.2016.00097.