The word ‘methylation’ has become somewhat of a buzz word in functional medicine. We’ve mentioned it several times throughout many episodes of The Lab Report – hard to avoid since it’s involved in just about every biological process.
In this episode, we finally hit the topic head on and dive into the methylation cycle itself. Although the biochemistry can be intimidating, listen as we simplify and demystify the steps involved and why each is important. You may find it helpful to refer to a Methylation Pathway Chart.
“It’s not the reaction that is significant, but how often the reaction is used in the body.” – Michael Chapman, ND
Today on The Lab Report:

2:00 What is methylation and why is it clinically important
5:30 Jumping into the biochemistry – metaphors to the rescue!
11:35 Homocysteine
14:00 The main pathway versus back up pathway
19:33 Transsulfuration
22:30 Multi-omics and the methylation cycle
27:50 Question of the Day

“What does it mean if homocysteine is low?”



Additional Resources:
Genova's Methylation Panel
Dr. Michael Chapman's Methylation Webinar
 
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