You might have heard the buzz around berberine, often referred to as “nature's Ozempic”.   Berberine is a powerhouse for many things, from reducing inflammation to regulating blood sugar levels. Tune in to hear which benefits the science supports (and the surprising ones it doesn’t) and get a simple dosing guide.  And if you have any additional questions you would like answered in the future, let me know in the comments!   Watch/Read Next… Diets Debunked: The Noom Program: https://drruscio.com/noom-debunked/  Diets Debunked: Weight Watchers: https://drruscio.com/weight-watchers/  Genetic Testing for Weight Loss Isn’t Worth it. Here’s what is: https://drruscio.com/genetic-testing-for-weight-loss/  How to Heal Your Gut Naturally: https://drruscio.com/how-to-heal-your-gut-naturally/     Timestamps 00:00 Intro  01:00 What is berberine?  01:37 Weight loss 02:34 Cholesterol 05:52 Blood sugar  08:47 Gut health  11:15 SIBO  12:53 Berberine dosing guide    Featured Studies  Biological properties and clinical applications of berberine: https://pubmed.ncbi.nlm.nih.gov/32335802/ Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders: https://pubmed.ncbi.nlm.nih.gov/30186157/  The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials: https://pubmed.ncbi.nlm.nih.gov/31915452/ The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials: https://pubmed.ncbi.nlm.nih.gov/32690176/ The effect of berberine supplementation on lipid profile and obesity indices: An umbrella review of meta-analysis: https://www.sciencedirect.com/science/article/abs/pii/S2213434423000361  Berberine decreases plasma triglyceride levels and upregulates hepatic TRIB1 in LDLR wild type mice and in LDLR deficient mice: https://pubmed.ncbi.nlm.nih.gov/31666640/  Berberine decreases cholesterol levels in rats through multiple mechanisms, including inhibition of cholesterol absorption: https://pubmed.ncbi.nlm.nih.gov/25002181/ Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/36941490/ Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials: https://pubmed.ncbi.nlm.nih.gov/31094214/ The Effect of Berberine on Metabolic Profiles in Type 2 Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/34956436/ Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/37598753/ Effects of berberine and barberry on selected inflammatory biomarkers in adults: A systematic review and dose-response meta-analysis of randomized clinical trials: https://pubmed.ncbi.nlm.nih.gov/37675930/ Berberine improves intestinal epithelial tight junctions by upregulating A20 expression in IBS-D mice: https://pubmed.ncbi.nlm.nih.gov/31306972/ Berberine Enhances Intestinal Mucosal Barrier Function by Promoting Vitamin D Receptor Activity: https://pubmed.ncbi.nlm.nih.gov/37046128/ Berberine influences multiple diseases by modifying gut microbiota: https://pubmed.ncbi.nlm.nih.gov/37599699/ Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner: https://pubmed.ncbi.nlm.nih.gov/26700862/ A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Pr