Carolina Reis Oliveira’s journey is as impressive as her expertise in skin care. In this episode, she dives deep into the science of skin aging. Along with Dr. Stephanie, she explores and explains both intrinsic and extrinsic factors, from cellular processes to environmental exposures. Carolina also shares insights into inflammation, peptide therapy, and the transformative potential of innovative compounds like OS1.Drawing from her team's research, Carolina discusses tangible results in reducing skin aging, offering hope for conditions like hyperpigmentation and rosacea. We explore strategies to stay ahead of the aging curve, aiming for what Carolina calls "escape velocity"—a state where we not only halt aging but reverse its effects.If you're curious about the latest advancements in skincare, eager to understand the mechanisms of aging, or simply looking to defy time gracefully, this episode is a must-listen. Uncover the keys to maintaining youthful, radiant skin and discover the future of skincare with Carolina Oliveira.Episode Overview:0:00 Intro/Teaser0:01:29 Interview with Carolina Oliveira0:03:10 Skin Aging Mechanisms and Peptide Therapy0:04:28 Intrinsic Mechanisms of Skin Aging0:08:21 Intrinsic Aging Factors and Genetics0:10:15 Cellular Senescence and Aging0:13:11 Autophagy and Aging0:14:37 Xenomorphic vs. Senolytic Compounds0:16:18 Discovery of OS1 Peptide0:19:12 Safety and Validation of OS1 Peptide0:20:53 Human Clinical Studies on OS1 Peptide0:25:00 Effects of OS1 on Skin Health0:29:31 Specific Formulations for Eye Cream0:31:01 Tailored Skincare for Different Areas of Body0:36:39 The Science of Hyperpigmentation and Skincare0:40:14 Combining Acids, Peptides, and Skincare0:44:15 Consumer Awareness and Integrity in Skincare0:47:57 The Importance of Antioxidants in Skincare0:51:52 The Future of Skincare: Lip Treatments0:53:43 Innovations in Sunscreen Technology0:56:53 Prioritizing Skin Health Over Immediate Results0:59:26 Maintaining Integrity in the Skincare IndustryBio:Carolina Oliveira, CEO and co-founder of OneSkin. Holds a Ph.D. in stem cell biology and tissue engineering, is a co-inventor of 5 patents and co-author of numerous scientific publications. She relocated from Brazil to Silicon Valley in 2016 to found OneSkin, a fast-growing longevity company developing products to promote skin age reversal by targeting a central driver of aging, the accumulation of senescent cells. Carolina and her team are disrupting the outdated anti-aging skincare industry with their groundbreaking research around skin and longevity.Resources mentioned:OneSkin: https://www.oneskin.co/About Carolina Reis Oliveira, Ph.D.: https://www.oneskin.co/pages/our-storyThe science: https://www.oneskin.co/pages/science and https://www.oneskin.co/pages/publicationsWe are grateful to our sponsors:EMBRI absolutely love this for my perimenopausal and menopausal women who are experiencing hot flashes and then the shivering that happens afterward. Go to https://embrlabs.com/products/embr-wave-2?rfsn=7896910.951991&discount/DRSTEPHANIE?redirect=/products/embr-wave-2 and use DRSTEPHANIE for 15% off of the Ember Wave 2. It is a bracelet (I got it in rose gold) and I love it.FATTY15Essential fatty acids create better skin, hair, nails, repair age-related damage to cells, and activate pathways that regulate sleep and mood. You can get an additional 15% off of their 90-day subscription starter kit if you go to https://fatty15.com/better and use code BETTER at checkout.BIOPTIMIZERSIf you want to get all your magnesium in one supplement, you will love Magnesium Breakthrough. Each supplement itself is 500 milligrams of magnesium, which I feel is such a great dosage as a great baseline for most women. So head on over to https://bioptimizers.com/better and use code BETTER for 10% off of any order, but make sure that the magnesium breakthrough is in your cart.