Here at Genova, we are incredibly proud of the high standards set by our laboratory director and the brilliant minds that work in the lab to keep things running smoothly. As clinicians, and consumers, many of us don’t give the inner workings of the lab a second thought. We take for granted that samples are sent, results are generated, and we can clinically act on those findings. Most of our profiles rely on several different laboratory methodologies to put the whole story together. One of those methods is called Chromatography – and clinicians don’t fully understand what that actually means.
In today’s episode, we call on our friend Ashley Gibbon – one of the smartest minds in laboratory science – to help us understand what chromatography is and why it is so vital to Genova testing.
Today on The Lab Report:
· 7:10 Ashley Gibbon defines chromatography
· 14:15 Organic acids and Separation science
· 16:15 The instrument – columns, beads, mobile and stationary phases
· 19:25 Detectors and mass spectrometry
· 23:15 Liquid vs. Gas chromatography
· 26:00 Maintaining the beads to preserve peaks
· 28:05 Quadrupoles, Sensitivity and specificity of detectors, and quantification
· 31:00 Area under the curve, inhibitors and interferents, coefficient of variance
· 34:00 Question of the Day
What is clinical vs. analytical sensitivity/specificity?
 
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Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guest
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