This episode examines the ongoing international negotiations over Iran’s nuclear programme, the implications of a potential nuclear agreement for security in the Middle East and Iran’s regional policies, and the likely future Middle East role of the United States and European powers. Dr.Tobias Borck, Research Fellow for Middle East Security Studies, and Darya Dolzikova, Research Fellow in Proliferation and Nuclear Policy programme, discuss with Dr Neil Melvin, Director, International Security Studies at RUSI, the efforts to revive the Joint Comprehensive Plan of Action (JCPOA) to regulate Tehran’s nuclear programme. The relationship between Iran’s nuclear activities and its regional security engagements is examined, together with a consideration of the possible future regional engagement by the United States and European states.