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What is Measuring Our Hba1c REALLY Telling Us About our Blood Glucose and Diabetes Risk? | Mastering Nutrition #12
What is Measuring Our Hba1c REALLY Telling Us About our Blood Glucose and Diabetes Risk? | Mastering Nutrition #12
ratings:
Length:
47 minutes
Released:
Jun 7, 2016
Format:
Podcast episode
Description
In response to popular demand, this week is glycation week. In this episode, I discuss the strengths and limitations of using Hba1c to measure our cumulative recent exposure to blood glucose and diabetes risk. Many people will be familiar with the fact that variation in red blood cell turnover confounds this measurement. Less well known is that variations in the deglycating enzyme fructosamine 3-kinase (FN3K) also confound the measurement. Counter-intuitively, if you have a higher rate of this deglycating enzyme but a lower rate of downstream metabolism of 3-deoxyglucosone, your lower Hba1c could actually mean MORE glycation. I conclude that Hba1c is a useful test, but only in the context of a bigger picture put together with more information.
Released:
Jun 7, 2016
Format:
Podcast episode
Titles in the series (100)
026: When Fat People Can't Get Fat Enough and Lean People Get Fat in All the Wrong Places: In episode 25, Insulin Resistance Isn't All About Carbs and Insulin, I explained why an individual cell would "decide" to stop taking up energy. Here in episode 26, I explain tissue-level energy overload, focusing on adipose tissue and liver. At... by Mastering Nutrition