This week we discuss a quick case leading into the management of MALA.


https://media.blubrry.com/coreem/content.blubrry.com/coreem/Podcast_Episode_124_0_Final_Cut.m4a



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Tags: Metformin, Toxicology





Show Notes
Take Home Points


In patients with shortness of breath and clear lungs, consider metabolic acidosis with respiratory alkalis as a potential cause
Suspect MALA in any patient on metformin who presents with abdominal pain, nausea and vomiting and/or AMS
Patients with MALA will have a low pH, a high-anion gap metabolic acidosis and high lactate levels
Call your tox consultant to assist with management which will focus on fluid resuscitation with isotonic bicarbonate and dialysis

Read More
Bosse GM. Antidiabetics and Hypoglycemics. In: Hoffman RS, Howland M, Lewin NA, Nelson LS, Goldfrank LR. eds. Goldfrank's Toxicologic Emergencies, 10e New York, NY: McGraw-Hill; 2015. Link Accessed October 31, 2017
LITFL: Metformin-Associated Lactic Acidosis
LITFL: Metformin
The Poison Review: