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362 -Cannabidiol (CBD) and Mental Health
Currently unavailable
362 -Cannabidiol (CBD) and Mental Health
ratings:
Length:
57 minutes
Released:
Feb 16, 2019
Format:
Podcast episode
Description
Cannabidiol: Mental Health Uses and Cautions
The CEU/OPD/CPD course can be found at https://allceus.com/member/cart/index/product/id/982/c/ for clinicians in the US and at https://australia.allceus.com/member/cart/index/product/id/516/c/ for clinicians in Australia.
Intro to CBD
~ THC is the psychoactive component of cannabis
~ THC has antispasmodic, analgesic, anti-tremor, anti-inflammatory, appetite stimulating and anti-emetic properties
~ High levels of THC is commonly used for its sleep-inducing effects
~ THC mimics the effects of anandamide and 2-AG (endogenous cannabinoid) which modulates sleeping and eating habits, the perception of pain
~ GABA neurons contain CBD receptors which are activated upon useof THC (and maybe CBD) https://www.royalqueenseeds.com/blog-the-link-between-marijuana-and-dopamine-n823
https://www.ncbi.nlm.nih.gov/pubmed/22625422
CBD cont…
~ CBD is the major nonpsychoactive component of Cannabis sativa.
~ According to a 2013 study published in the British Journal of Clinical Pharmacology, CBD benefits include acting as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic, neuroprotective, immunomodulatory and antipsychotic effects
~ A biphasic drug has different effects on the body at different blood concentration levels.
~ Ex. Alcohol acts as a stimulant until BAC levels reach 0.05%. After this point it causes sedation and depression
~ At a low concentration CBD increases wakefulness, alertness and other elevating responses.
~ At higher levels CBD has a sedating effect
CBD cont…
~ 36% of respondents reported that CBD treats their medical condition(s) “very well by itself,” while only 4.3% reported “not very well.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043845/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/
The Cannabinoid Receptors
~ CBD and THC both bind to the CB 1 & 2 receptors, they interact with them different ways
~ CB1 and CB2 are both responsible for regulating neuro-hormones which are involved in memory, mood, sensations of pain and appetite regulation
~ CB1
~ Found in the CNS and responds to endogenous cannabinoids, as well as THC (agonist) and CBD (mild antagonist).
~ Abundant in areas of the brain concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine (hormone) functions
The Cannabinoid Receptors
~ CB2
~ Found only in the immune system and not in the CNS, but seems to reduce inflammation and related pain.
~ It responds to endogenous cannabinoids, as well as CBD, THC
Alcohol and CBD
~ The CB1 receptor is a significant player in the reinforcing and motivating attributes of alcohol. Combining alcohol and CBD results in significantly lower blood levels of alcohol.
~ CBD reduces the reinforcement, motivation and relapse for alcohol.
~ CBD attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury.
~ Cannabinoids have an effect on nearly all enzymes responsible for metabolizing alcohol.
~ Cannabinoid antagonists also mitigate alcohol withdrawal symptoms.
~ CB1 receptor agonists (THC) encourage alcohol consumption, while CB1 receptor antagonists (CBD) decrease it.
Benefits of CBD
~ According to the National Institute of Health, manipulating the endocannabinoid system by introducing external cannabinoids like CBD could be useful in treating a variety of medical ailments, including:
How CBD Impacts Mood
~ CBD can help people recover from Clostridium difficile toxin A toxicity and restore the intestinal barrier* https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57
The CEU/OPD/CPD course can be found at https://allceus.com/member/cart/index/product/id/982/c/ for clinicians in the US and at https://australia.allceus.com/member/cart/index/product/id/516/c/ for clinicians in Australia.
Intro to CBD
~ THC is the psychoactive component of cannabis
~ THC has antispasmodic, analgesic, anti-tremor, anti-inflammatory, appetite stimulating and anti-emetic properties
~ High levels of THC is commonly used for its sleep-inducing effects
~ THC mimics the effects of anandamide and 2-AG (endogenous cannabinoid) which modulates sleeping and eating habits, the perception of pain
~ GABA neurons contain CBD receptors which are activated upon useof THC (and maybe CBD) https://www.royalqueenseeds.com/blog-the-link-between-marijuana-and-dopamine-n823
https://www.ncbi.nlm.nih.gov/pubmed/22625422
CBD cont…
~ CBD is the major nonpsychoactive component of Cannabis sativa.
~ According to a 2013 study published in the British Journal of Clinical Pharmacology, CBD benefits include acting as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic, neuroprotective, immunomodulatory and antipsychotic effects
~ A biphasic drug has different effects on the body at different blood concentration levels.
~ Ex. Alcohol acts as a stimulant until BAC levels reach 0.05%. After this point it causes sedation and depression
~ At a low concentration CBD increases wakefulness, alertness and other elevating responses.
~ At higher levels CBD has a sedating effect
CBD cont…
~ 36% of respondents reported that CBD treats their medical condition(s) “very well by itself,” while only 4.3% reported “not very well.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043845/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/
The Cannabinoid Receptors
~ CBD and THC both bind to the CB 1 & 2 receptors, they interact with them different ways
~ CB1 and CB2 are both responsible for regulating neuro-hormones which are involved in memory, mood, sensations of pain and appetite regulation
~ CB1
~ Found in the CNS and responds to endogenous cannabinoids, as well as THC (agonist) and CBD (mild antagonist).
~ Abundant in areas of the brain concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine (hormone) functions
The Cannabinoid Receptors
~ CB2
~ Found only in the immune system and not in the CNS, but seems to reduce inflammation and related pain.
~ It responds to endogenous cannabinoids, as well as CBD, THC
Alcohol and CBD
~ The CB1 receptor is a significant player in the reinforcing and motivating attributes of alcohol. Combining alcohol and CBD results in significantly lower blood levels of alcohol.
~ CBD reduces the reinforcement, motivation and relapse for alcohol.
~ CBD attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury.
~ Cannabinoids have an effect on nearly all enzymes responsible for metabolizing alcohol.
~ Cannabinoid antagonists also mitigate alcohol withdrawal symptoms.
~ CB1 receptor agonists (THC) encourage alcohol consumption, while CB1 receptor antagonists (CBD) decrease it.
Benefits of CBD
~ According to the National Institute of Health, manipulating the endocannabinoid system by introducing external cannabinoids like CBD could be useful in treating a variety of medical ailments, including:
How CBD Impacts Mood
~ CBD can help people recover from Clostridium difficile toxin A toxicity and restore the intestinal barrier* https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57
Released:
Feb 16, 2019
Format:
Podcast episode
Titles in the series (100)
013- What are Co-Occurring Disorders and How Do They Impact Treatment Part 2: Many people struggling with addictions also have mental health issues such as depression or anxiety. Likewise, many people with depression or anxiety may have an addiction. We refer to this as a co-occurring disorder. Some people will try to argue that s by Counselor Toolbox Podcast with DocSnipes