Fascinating GU Cast today focussing on the role of MRI scanning for patients on active surveillance (AS) for prostate cancer. We are joined by two of the world's leading experts on prostate MRI to discuss two recent systematic reviews on this topic.  Professor Anwar Padhani, Radiologist at Mt Vernon Cancer Centre and the Institute of Cancer Research  in London, and Professor Caroline Moore, Urologist at University College London, give some fascinating insights and tackle some controversial questions. Patients and clinicians would love to avoid further biopsies as part of active surveillance monitoring. However, repeat biopsy remains a strong recommendation in all AS guidelines. Anwar reviews the two recent systematic reviews (links below), plus his recent European Urology editorial, and Caroline reveals what they currently offer patients at UCL (spoiler alert - they don't do routine biopsies on AS)! Anwar also introduces the very valuable work of the International Cancer Imaging Society, and we talk about the fantastic collection of talks he posts on his very popular YouTube channel. Links all below. Usual hosts Declan Murphy and Renu Eapen. Enjoy! Links:Eur Urol systematic reviewEur Urol Oncol systematic reviewAnwar's Editorial in Eur UrolAnwar's YouTube channelInternational Cancer Imaging SocietyAnwar's twitterCaroline's twitter