We hijacked our good friends Professor Boris Hadaschik (Urologist, Essen, Germany), and Associate Professor Tyler Seibert (Radiation Oncologist, University of California, San Diego), who happened to be in Melbourne this week, and diverted them into the GU Cast studio for a chat about high-risk prostate cancer. Boris and Tyler were on a speaker tour supported Janssen Pharmaceuticals, so we put together this Themed Podcast supported by Janssen (Gold Partners of GU Cast), to probe three key questions in high-risk prostate cancer in 2023:1. What is the role of PSMA PET/CT in initial staging? 2. If the PSMA PET/CT is N0, can we avoid pelvic lymph node dissection?3. What is the optimal radiotherpay strategy for high-risk prostate cancer in 2023?Superb multidisciplinary chat with two great experts. Thanks to Janssen for their support for this Themed Episode of GU Cast. Even better on our YouTube channel Twitter links:Boris Hadaschik Tyler Seibert