Dr Glenn McConell chats with Professor David Bishop from Victoria University in Melbourne, Australia. He has a broad background in exercise physiology research and has focused for many years on exercise and muscle mitochondria. He finds that low volume, prolonged exercise tends to increase mitochondrial volume more than mitochondrial function while sprint exercise training does the opposite, increasing mitochondrial function more than mitochondrial volume. He hypothesizes that polarized type training may be best to get increases in both mitochondrial function and mitochondrial volume. A very interesting chat. David’s Twitter: @BlueSpotScience0:00. Introduction2:45. Defining the different training zones4:30. More to being an endurance athlete than the mitochondria6:15. Intensity vs volume for mitochondrial responses8:30. Dissociations between mito function and mito volume10:35. Mechanisms involved?Takeaway messages12:05. Issues with normalizing mitochondrial findings?15:20. Applying results at rest, in recovery to during exercise18:00. Isolated mito results correlate with NMR?18:50. Polarized training best to get both mito function and volume?23:30. Can’t assume signaling etc changes affect performance27:35. Determinants of exercise performance28:50. Lactate threshold and mitochondrial function32:15. Training volume most important for mito content33:20. Overtraining vs energy deficit36:05. Should tailor training based on VO2 max?38:35. VO2 max vs lactate threshold40:00. VO2 max and running economy not linked?44:20. Resting vs maximum heart rate45:45. Sodium bicarbonate, lactate, training and mitochondria49:46. Is training specificity overrated?55:15. Interval training work: rest ratios58:20. High intensity interval training and mito damage1:01:30. Need lab testing?1:05:10. Important to be concerned about training zones?1:07:55. Tends to be in polarized training camp1:11:55. Considering the needs/physiology of the event/sport1:15:30. Takeaway messagesOutro (9 seconds)1:17:10. Dividing the mito function per mg of muscle1:21:15. Outro (9 seconds)Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).Connect with Inside Exercise and Glenn McConell at:Twitter: @Inside_exercise and @GlennMcConell1Instagram: insideexerciseFacebook: Glenn McConellLinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460ResearchGate: Glenn McConellEmail: glenn.mcconell@gmail.comSubscribe to Inside exercise:Spotify: shorturl.at/tyGHLApple Podcasts: shorturl.at/oFQRUYouTube: https://www.youtube.com/@insideexerciseAnchor: https://anchor.fm/insideexerciseGoogle Podcasts: shorturl.at/bfhHIAnchor: https://anchor.fm/insideexercisePodcast Addict: https://podcastaddict.com/podcast/4025218Not medical advice