There were some exciting and clinically meaningful research in scleroderma/systemic sclerosis presented by experts at the American College of Rheumatology (ACR) Convergence 2021. Tracy Frech, MD, provides a comprehensive overview of the studies presented at the ACR meeting this year, by categorizing them into 5 categories: practice pearls, treatment updates, pediatrics, outcome measures, and COVID-19-related research.