Pediatric rheumatologists and providers are uniquely positioned to build and foster relationships of trust with their patients. However, while providing care for the rheumatic condition, should physicians be allowed to inquire about the sexual orientation and gender identity of their patients? In this episode, we tackle important questions about the ethical considerations during the development of treatment plans for pediatric patients with rheumatic diseases. Karen Onel, MD, the chief of the Pediatric Rheumatology Division at the Hospital for Special Surgery, New York, along with third-year fellows in pediatric rheumatology Nayimisha Balmuri, MD, and Jacob Spitznagle, MD, speak with us about their clinical practice experiences and the importance of representing pediatric patients in a way that centers and considers their personhood holistically, especially among populations in which mental health issues and other psychosocial stressors are present.