Imaging is an important aspect in the diagnosis and monitoring of large vessel vasculitides, including Takayasu and giant cell arteritis. However, traditional imaging modalities have consistently posed setbacks in terms of diagnostic accuracy for these conditions. Our featured guest on this episode Anisha Dua, MD, gives us a brief insight into the various challenges observed with large vessel vasculitis imaging, particularly temporal artery biopsy, and how the inclusion of certain modalities, including ultrasound and magnetic resonance imaging (MRI), may improve diagnosis in these patients and our understanding of large vessel vasculitis.