In this episode of Quantitude, Patrick and Greg have the pleasure of talking with the always-entertaining and high-energy Don Hedeker, University of Chicago Professor of Biostatistics. They discuss Don's work in nonlinear mixed effects models, the importance of variance as an outcome, and ecological momentary assessment, as well as his advice for graduate students and indeed anyone presenting and writing in our field. Also mentioned in this episode are: getting scooped, day jobs, the Brady bunch, German parents, midlife crises, beer salesmen, putting a nail through a fish, The Ramones, Anarchy in the UC, and sneaking into hotel rooms. Come for the stats, stay for the polka-infused rock and roll!