Most people assume that itchiness means there’s too much histamine in their bodies. This assumption is often very wrong leading people to take anti-histamine medications that they will admit don’t help much. If this hits home, you’ll be shocked to know that there are many different reasons (or hidden root causes) that can drive itch that often isn’t explored in conventional dermatology. So if you’re frustrated that nothing seems to help that awful itch, you’re in the right place! In this episode: MYTH-BUSTING – itchiness + histamine intolerance Common meds + supplements used to stop itch What happens when these options don’t work? Different itch triggers (that have nothing to do with histamine) What about chronic hives + dermatographia? Quotes: If itchiness were solely triggered by histamine, then the medications and even potentially the supplements would help. Itchiness is associated with higher levels of IL-31 in the body (especially in those with eczema, urticaria, and prurigo nodularis).