What we're talking about in this episode! How to ignite your metabolism and prolong your longevity through diet and lifestyle Learn how your metabolism works on a biological and evolutionary level A look back at the traditions of supercentenarians diet and foraging habits  The most beneficial and simple lifestyle and nutrition switches that make a difference Explore the benefits of intermittent fasting, the ketogenic diet, and more   Episode Summary:  Did you know that our cells have the ability to clean themselves, remove debris and self-regulate to get back to optimal functioning? This process is called cellular autophagy and is something that my guest today, James Clement, is very familiar with.  After launching a study around supercentenarians, or people that live over the age of 110, James realized the direct link between cellular autophagy, increased metabolism and an undeniable increase in longevity. James decided to put this discovery into his new book, The Switch, to help both doctors and patients understand how to harness the incredible evolutionary self-preservation mechanism.  Cellular autophagy is like hitting the reset button for your body and can optimize your biological function, minimize disease and help you achieve a lifespan you never thought possible. Through a simple diet, nutrition and lifestyle changes, you can turn your autophagy switch on and reap the amazing benefits that your body already possesses.  How are you working to increase your longevity and boost your metabolism naturally? Share your thoughts in the comment section on the episode page.   Quotes: “Metabolism refers to the chemical processes that go on inside our cells, basically that maintain all of our life processes. And in order to really understand it, you have to look at our evolutionary history.” (10:50) “Life has really changed dramatically in the past 150 years, and some of this is to our healths detriment.” (16:46) “One of the things that we found with most of these supercentenarians, people who lived to 110 years and beyond, is that they won a genetic lottery that the rest of us just don’t have. And their relatives are 17 times more likely to make it to 100 than the rest of us too, so it is an inheritable genetic mutation. But for the rest of us, lifestyle makes up 90% of our health risk and longevity, and that’s where most of us need to focus” (20:39) “The easiest thing for people to do is to break into this ketogenic diet lifestyle. They can switch in and out of it, cycle in and out of this keto, but just turning it on, even infrequently, allows your body to re-learn how to burn fat.” (25:02) “We have to turn this on to keep healthy, and if we don’t, we do that at our peril. (30:34)   Resources Mentioned: The Switch by James Clement  Better Humans Website EY 155: How To Create Your Perfect Day With 20/20 Vision   Other Resources: Check out the full show notes page Keep up with everything Dr. Mariza Follow Dr. Mariza on Facebook | Instagram | Twitter | Youtube