Anxiety and Dysautonomia: Do I Have POTS or Autonomic Dysfunction?
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About this ebook
Anxiety is a component of many physical and mental disorders, from depression to PTSD. Unfortunately, not many patients find relief in the associated therapies and medications, and simply adding more of the same often causes other disorders. Additionally, many who suffer from anxiety may in fact have other, anxiety-like conditions, such as the frequently misdiagnosed postural orthostatic tachycardia syndrome (POTS), which can make any attempt at treatment futile.
But now, with Anxiety and Dysautonomia: Do I Have POTS or Autonomic Dysfunction?, Donald J. Parker and physicians Joseph Colombo and Nicholas L. DePace aim to show, with a simplified analysis and discussion focusing on this common patient complaint and how best to treat it, that no longer does anxiety need to be merely managed with the forced lifestyle changes that are often required. Topics covered include:
- Parasympathetic and Sympathetic (P&S) dysfunctions that lead to anxiety-like conditions, plus clear concepts of anxiety and anxiety-like symptoms, the six-pronged Mind-Body Wellness Program, and the P&S nervous systems.
- How many of these anxiety-like conditions are actually caused by a lack of proper blood flow to the brain, which may cause mild symptoms of depression, fatigue, malaise, brain fog, and cognitive and memory difficulties, sleep difficulties, and more.
- The way these issues, when exacerbated, may trigger “adrenaline storms” that cycle the anxiety-like symptoms.
- Treatments that in many cases enable a return to a “normal” (as defined by the patient) quality of life, including natural therapies to relieve symptoms and promote wellness.
Read more from Nicholas L. De Pace
Fatigue and Dysautonomia: Chronic or Persistent, What's the Difference? Rating: 0 out of 5 stars0 ratingsClinical Autonomic and Mitochondrial Disorders: Diagnosis, Prevention, and Treatment for Mind-Body Wellness Rating: 0 out of 5 stars0 ratings
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Anxiety and Dysautonomia - Nicholas L. DePace
Copyright © 2022 by Nicholas L. DePace, Donald J. Parker, and Joe Colombo
All Rights Reserved. No part of this book may be reproduced in any manner without the express written consent of the publisher, except in the case of brief excerpts in critical reviews or articles. All inquiries should be addressed to Skyhorse Publishing, 307 West 36th Street, 11th Floor, New York, NY 10018.
Skyhorse Publishing books may be purchased in bulk at special discounts for sales promotion, corporate gifts, fund-raising, or educational purposes. Special editions can also be created to specifications. For details, contact the Special Sales Department, Skyhorse Publishing, 307 West 36th Street, 11th Floor, New York, NY 10018 or info@skyhorsepublishing.com.
Skyhorse® and Skyhorse Publishing® are registered trademarks of Skyhorse Publishing, Inc.®, a Delaware corporation.
Visit our website at www.skyhorsepublishing.com.
10 9 8 7 6 5 4 3 2 1
Library of Congress Cataloging-in-Publication Data is available on file.
ISBN: 978-1-5107-6090-5
eBook: 978-1-5107-6118-6
Cover design by Kai Texel
Printed in the United States of America
TABLE OF CONTENTS
(a ‘D’ at the beginning of a table of content entry indicates a section specifically on the Physician side (‘D’ for Doctor), a ‘P’ indicates a section specifically on the Patient side)
CONTENT FORMAT
INTRODUCTION
Background
Mind-Body Wellness Program Basics
Parasympathetic and Sympathetic (P&S) Monitoring
Disclaimer
ANXIETY
History
Anxiety and Dysautonomia
Definitions and Diagnoses
(D) Anxiety Intervention
(P) Helpful Hints and Concepts
(D) Supplements and Lifestyle Modification Therapy: The Mind-Body Wellness Program
(D) Pharmacological Therapy For P&S Anxiety: Homeopathic Levels
(P) Reasons Why You May Have Been Misdiagnosed or Poorly Managed
(P) Anxiety and Depression
(D) Anxiety Risks: Depression and Suicide
Neurofeedback
Best to Avoid
CONTENT FORMAT
After the Introduction (including the Background, Mind-Body Wellness Program Basics, Parasympathetic and Sympathetic (P&S) Monitoring, and Disclaimers), the main body of the book is written in two parts (see the next two pages as the example): one part to the patient or the patient’s loved ones and one part to the physicians. The patient part is written on the right hand page (the odd-numbered pages) and the physician part is written on the left hand page (the even-numbered pages). Essentially the same information is presented in both parts, just using different styles (languages
) to communicate the information. In this way, patients (if interested) may see what the doctors may be, or as we believe should be, considering, and the physicians will have an example of a way of communicating with their patients, especially in this field that is poorly understood and even less well taught.
FOR PHYSICIANS
Most left hand (or even-numbered) pages are written for Physicians.
While other Dysautonomia books explain how to manage patients with autonomic dysfunction, we look to provide more information to help physicians treat autonomic dysfunction (aka., Dysautonomia). Furthermore, assuming no end-organ damage or genetic causes, we believe the recommendations herein will help physicians to work with their patients to restore health and even wellness, if certain lifestyles are adopted.
This book will lean heavily towards supplements and lifestyle treatments for Anxiety and Dysautonomia. The primary reason is that there are only two pharmaceuticals (Midodrine and Northera) approved for autonomic dysfunction. All other pharmaceuticals that are recommended are off-label recommendations. In fact, there are now more supplements and lifestyles recommended in large, multi-center studies for Dysautonomia (including dosing; e.g., Alpha-Lipoic Acid, Fish Oil, Co-Enzyme Q10, and Exercise) than approved pharmaceuticals.
Another reason is that, in our experience, by the time a patient see us, they have been prescribed many mediations and in high dosages. Therefore, they have become intolerant or unresponsive to the few medications that we have found to work, but in very low dosages. The supplements and lifestyle modifications aid in enabling dosing of the pharmaceuticals in low or homeopathic dosages, and the pharmaceuticals are then able to help accelerate the relief brought about by the supplements and lifestyle modifications. In many cases, the goal is to eventually wean from the pharmaceuticals and maintain with lower dose supplements and continued lifestyle modifications.
We include information to enable the physician to provide:
Thorough clinical assessments,
Patient education upon diagnosis,
Assistance with interpreting and understanding the results of P&S Monitoring, and
Possible therapy options, including short-term, long-term, and life-long.
The primary basis for this book is the science text: DePace NL and Colombo J. Clinical Autonomic and Mitochondrial Disorders – Diagnosis, Prevention, and Treatment for Mind-Body Wellness. Springer Science + Business Media, New York, NY, 2019.
For a more in-depth discussion on P&S Monitoring consider the science text: Colombo J, Arora RR, DePace NL, Vinik AI. Clinical Autonomic Dysfunction: Measurement, Indications, Therapies, and Outcomes. Springer Science + Business Media, New York, NY, 2014. This book focusses on the science of Fatigue in a less formal style.
Enjoy!
FOR PATIENTS AND THEIR LOVED ONES
Most right hand (or odd-numbered) pages are written for Patients.
While other Dysautonomia books explain how patients should live with autonomic dysfunction (aka., Dysautonomia), we look to help you to overcome your Dysautonomia and associated Anxiety. As we have helped countless numbers of patients in the past, we hope to help you to reclaim your life by improving your quality of life and reducing the numbers of symptoms, medications, and costs associated with Anxiety.
As we have, and continue to do, these general therapy recommendations must be tailored specifically to you the individual patient. Therefore, the recommendations herein are not one-size fits all.
They must be considered by your Physician specifically for you in light of your individual medical and personal history. Please do not consider any statement in this book as a diagnosis or prescribed therapy plan. These are guidelines to help educate. Again, THE INFORMATION IN THIS BOOK MUST BE CONSIDERED BY A PHYSICIAN AND APPLIED BY A PHYSICIAN BASED ON YOUR CLINICAL HISTORY.
Yes, there are pharmaceuticals recommended, and yes, we understand that many of you have been medicated to death
and, as a result, no longer tolerate many medications that we may recommend. However, please understand that the dosages of pharmaceuticals are very low, and in most cases, homeopathic. Plus, the pharmaceuticals are recommended to help accelerate the relief that is usually brought about by the supplements and lifestyle modifications.
We hope that the information contained herein will restore hope for a better life and faith in the healthcare system, to enable you to work with your physician toward wellness. While not everyone, we have indeed helped most patients become active again and return to being a contributor to society. This is not to say that you may not need therapy life-long. In fact, some do. However, the therapy may not require pharmaceuticals.
We include information to educate the patient so that they may help their physician and achieve health and wellness. To this end, we explain:
How the P&S branches of the autonomic nervous system should work together in balance,
How Dysautonomia (P&S imbalance) contributes to your symptoms of Anxiety,
Why you may not have been properly diagnosed in the past,
The clinical differences between Anxiety and Anxiety-like disorders,
What to expect in working with your physician, and
How to help.
Be Well!
INTRODUCTION
Our first book in this series is about Fatigue, both Chronic Fatigue Syndrome and what we call Persistent Fatigue. Persistent Fatigue refers to all those who are complaining of fatigue that do not fit the definition of Chronic Fatigue Syndrome. We wrote about Fatigue first because, in our experience, Fatigue is the most commonly complained-about symptom. However, in our experience, Anxiety or rather (as we will define) Anxiety-like disorder is the most commonly diagnosed disorder. Like Persistent Fatigue, Anxiety-like disorders are those patients who report symptoms of Anxiety but do not fit the definition of Anxiety. In fact, there is evidence that diagnoses of Anxiety, including what we call Anxiety-like disorders, are the most diagnosed condition world-wide – more diagnosed than heart disease and diabetes combined [1].
Background
The Strict Definition of Anxiety
The American Psychiatric Association (APA) classifies many psychological disorders under the umbrella of Anxiety. The classification that most people think of as Anxiety
is Generalized Anxiety Disorder (GAD). From the APA’s Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5, 2013), the clinical definition of GAD is:
Excessive anxiety and worry (apprehensive expectation), occurring more days than not for at least 6 months, about a number of events or activities (such as work or school performance).
The individual finds it difficult to control the worry.
The anxiety and worry are associated with three (or more) of the following six symptoms (with at least some symptoms having been present for more days than not for the past 6 months): Note: Only one item is required for children.
Restlessness, feeling keyed-up or on edge.
Being easily fatigued.
Difficulty concentrating or mind going blank.
Irritability.
Muscle tension.
Sleep disturbance (difficulty falling or staying asleep, or restless, unsatisfying sleep).
The anxiety, worry, or physical symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.
The disturbance is not attributable to the physiological effects of a substance (e.g., a drug of abuse or a medication) or another medical condition (e.g., hyperthyroidism).
The disturbance is not better explained by another medical disorder (e.g., anxiety or worry about having panic attacks in Panic Disorder, negative evaluation in Social Anxiety Disorder [Social Phobia], contamination or other obsessions in Obsessive-Compulsive Disorder, separation from attachment figures in Separation Anxiety Disorder, reminders of traumatic events in Post-Traumatic Stress Disorder, gaining weight in Anorexia Nervosa, physical complaints in Somatic Symptom Disorder, perceived appearance flaws in Body Dysmorphic Disorder, having a serious illness in Illness Anxiety Disorder, or the content of delusional beliefs in Schizophrenia or Delusional Disorder).
The DMS-5 is the APA’s text listing and describing all of the current recognized psychiatric disorders. In addition to GAD, they include Social Anxiety Disorder, Selective Mutism in Children, Panic Disorder, Agoraphobia and other Specific Phobias, Separation Anxiety Disorder, and Illness Anxiety Disorder. In the most recent definition of Anxiety disorders, the APA removed Post-Traumatic Stress Disorder and Obsessive-Compulsive Disorder and listed them on their own, along with other related disorders. Attention Deficit Disorder, Attention Deficit and Hyperactivity Disorder, Bipolar Disorder and other Depression-Anxiety disorders, and Manic Disorders, including Manic/Depression Disorder, are all known to also involve anxiety.
YOU MAY NOT FIT THE STRICT DEFINITION.
THERE ARE MANY PATIENTS THAT DO NOT FIT THESE SPECIFIC CRITERIA.
THIS MAY BE YOU!
Based on the first book in this Mind-Body Wellness series (FATIGUE & Dysautonomia: Chronic or Persistent, What’s the Difference? The Mind-Body Wellness Program, Skyhorse, 2020), we generalize Item C.2. (Fatigue)
to include both chronic fatigue, as in Chronic Fatigue Syndrome (CFS), and Persistent
Fatigue, as in all the other fatigue patients that do not fit the specific APA criteria. Also, we generalize Item C.3. (Difficulty concentrating or mind going blank)
to include Brain-Fog,
difficulty finding words, as well as cognitive and memory difficulties typically associated with fatigue and the Dysautonomias that are associated with fatigue.
It may not all in your head.
Anxiety disorders, and disorders having anxiety-laden symptoms as part of their presentation (what we will term Anxiety-like
Disorders), affect millions of Americans at any given time, and many millions world-wide, and the numbers are growing rapidly. Anxiety, regardless of its form, may be more of a healthcare issue than people are willing to realize, and the effects are more insidious and pernicious. Anxiety disorders cause significant interpersonal, occupational, and economic burdens for the patients afflicted; and the family, friends and loved ones of those patients; and society as a whole, including businesses, schools, and governments. Given the fear-mongering of the news media, weather reporters, advertisers, and even the government, any form of anxiety will amplify