Life And Death Of A Skin Cell (Skin Man)
By Kenneth Kee
()
About this ebook
My name is Skin Man the Skin Cell.
I was named Skin Man by my friends who feel that Skin Man is the name of a cell from the largest organ of the human body.
The only cells in the early human embryo are precursor cells or stem cells that are nudged into becoming specialized bone, nerve, internal organ or skin cells by the action of genes and the growth-and-development molecules produced by genes.
It may be surprising to learn that we skin cells have a developmental relationship with many others tissues such as breast and prostate gland but this shows the built-in potential of stem cells to grow into a variety of specialized forms.
We Skin cells do not just spring into existence from embryo stem cells.
The path of our development begins in a group of stem cells that are nudged into different directions to become specialized cells of many different tissues and organs including skin.
The paraxial mesoderm is divided along the embryo's length into somites, corresponding to the segmentation of the body.
1. Sclerotome (which forms vertebrae),
2. Dermatome (which forms skin), and
3. Myotome (which forms muscle).
It has long been known that we skin cell development begins in the dermatome of the very early embryo before the embryo begins to mature into the recognizably human form of a fetus.
The skin is the largest organ of the body with a total area of about 20 square feet.
My skin protects us from microbes and the elements, helps regulate body temperature, and permits the sensations of touch, heat, and cold.
My Skin has three layers:
The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.
The dermis, beneath the epidermis, contains tough connective tissue, hair follicles, and sweat glands.
The deeper subcutaneous tissue (hypodermis) is made of fat and connective tissue.
My skin’s color is created by my special cells called melanocytes which produce the pigment melanin.
My melanocytes are located in the epidermis.
Melanin produced by my melanocytes comes in two types:
1. Pheomelanin (red)
2. Eumelanin (dark brown to nearly black).
Red and brown pigments are in our skin cells.
My actual skin color is just going to be a mix of these colors in varying degrees.
Having a higher concentration of these colors means that the melanins are closer together and my skin is darker.
People that are even closely related can have different skin tones.
There is a difference in skin color in people all around the world.
This is important as skin color can give rise to discrimination between people of various skin colors such as so-called white supremacy.
Sometimes the absence of my melanocytes result in melanin being produced and an albino is the result –white hair and pale skin.
My Skin cells are constantly being regenerated.
I was born in the lower layer of the skin called the dermis, which is supplied with blood vessels and nerve ending.
My skin cell migrates upward for about two weeks until it reaches the bottom portion of the epidermis, which is the outermost skin layer.
The epidermis does not have blood vessels but does have nerve endings.
My skin cell spends another two weeks in the epidermis gradually flattening out and continuing to move toward the surface.
There I will die and will be shed.
TABLE OF CONTENT
Chapter 1 Story of Skin Man
Chapter 2 Life Cycle of Skin Cell
Chapter 3 Formation of a Skin Cell
Chapter 4 Death of a Skin Cell
Chapter 5 Eczema
Kenneth Kee
Medical doctor since 1972.Started Kee Clinic in 1974 at 15 Holland Dr #03-102, relocated to 36 Holland Dr #01-10 in 2009.Did my M.Sc (Health Management ) in 1991 and Ph.D (Healthcare Administration) in 1993.Dr Kenneth Kee is still working as a family doctor at the age of 74However he has reduced his consultation hours to 3 hours in the morning and 2 hours inthe afternoon.He first started writing free blogs on medical disorders seen in the clinic in 2007 on http://kennethkee.blogspot.com.His purpose in writing these simple guides was for the health education of his patients which is also his dissertation for his Ph.D (Healthcare Administration). He then wrote an autobiography account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.comThis autobiography account “A Family Doctor’s Tale” was combined with his early “A Simple Guide to Medical Disorders” into a new Wordpress Blog “A Family Doctor’s Tale” on http://ken-med.com.From which many free articles from the blog was taken and put together into 1000 eBooks.He apologized for typos and spelling mistakes in his earlier books.He will endeavor to improve the writing in futures.Some people have complained that the simple guides are too simple.For their information they are made simple in order to educate the patients.The later books go into more details of medical disorders.He has published 1000 eBooks on various subjects on health, 1 autobiography of his medical journey, another on the autobiography of a Cancer survivor, 2 children stories and one how to study for his nephew and grand-daughter.The purpose of these simple guides is to educate patient on health disorders and not meant as textbooks.He does not do any night duty since 2000 ever since Dr Tan had his second stroke.His clinic is now relocated to the Buona Vista Community Centre.The 2 units of his original clinic are being demolished to make way for a new Shopping Mall.He is now doing some blogging and internet surfing (bulletin boards since the 1980's) startingwith the Apple computer and going to PC.The entire PC is upgraded by himself from XT to the present Pentium duo core.The present Intel i7 CPU is out of reach at the moment because the CPU is still expensive.He is also into DIY changing his own toilet cistern and other electric appliance.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"
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Life And Death Of A Skin Cell (Skin Man) - Kenneth Kee
Life
And
Death
Of
A
Skin
Cell
(Skin Man)
By
Dr Kenneth Kee
M.B., B.S. (Singapore)
Ph.D (Healthcare Administration)
Copyright Kenneth Kee 2014 Smashwords Edition
Published By Kenneth Kee at Smashwords.com
Dedication
This book is dedicated
To my wife Dorothy
And my children
Carolyn, Grace
And Kelvin
This book describes the story of the one Skin Cell (Skin Man) from its birth to its death in the human body.
This eBook is licensed for your personal enjoyment only. This eBook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each reader.
If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy.
Thank you for respecting the hard work of this author.
Chapter 1
MY STORY as a Skin Cell
My name is Skin Man the Skin Cell.
I was named Skin Man by my friends who feel that Skin Man is the name of a cell from the largest organ of the human body.
The only cells in the early human embryo are precursor cells or stem cells that are nudged into becoming specialized bone, nerve, internal organ or skin cells by the action of genes and the growth-and-development molecules produced by genes.
It may be surprising to learn that we skin cells have a developmental relationship with many others tissues such as breast and prostate gland but this shows the built-in potential of stem cells to grow into a variety of specialized forms.
We Skin cells do not just spring into existence from embryo stem cells.
The path of our development begins in a group of stem cells that are nudged into different directions to become specialized cells of many different tissues and organs including skin.
The paraxial mesoderm is divided along the embryo's length into somites, corresponding to the segmentation of the body.
1. Sclerotome (which forms vertebrae),
2. Dermatome (which forms skin), and
3. Myotome (which forms muscle).
It has long been known that we skin cell development begins in the dermatome of the very early embryo before the embryo begins to mature into the recognizably human form of a fetus.
The skin is the largest organ of the body with a total area of about 20 square feet.
My skin protects us from microbes and the elements, helps regulate body temperature, and permits the sensations of touch, heat, and cold.
My Skin has three layers:
The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.
The dermis, beneath the epidermis, contains tough connective tissue, hair follicles, and sweat glands.
The deeper subcutaneous tissue (hypodermis) is made