Dr. Mark Holthouse returns to The Thorne Podcast to discuss mitochondrial uncoupling to generate heat and burn fat. Listen in to learn how this process can promote healthy aging and how the powerhouse of the cell reacts to oxidative stresses in the body.
During this episode you’ll learn about:
Mark Holthouse’s 30 years of practice [0:59]
Mitochondrial uncoupling: What role does it play in longevity? [3:30]
How mitochondria are “little furnaces” for fat burning [6:19]


Cold water and red light therapies help with uncoupling [10:58]
Ketones as a signaling agent for fat burning [13:16]
A plant-based diet promotes mitochondrial uncoupling [14:48]


Oxidative stress and free radicals: The good, the bad, the not-so bad for mitochondria? [17:30]
Questions from the community [23:28]
Why does mitochondrial biogenesis slow down over time? [23:42]
What age do we start losing mitochondria? [28:50]
How can I improve my mitochondrial health? [34:57]
What does NAD have to do with all this? [38:35]
How long do I need the fast to stimulate my mitochondria? [44:03]



Resources to topics mentioned in this episode:
Can Your Body Keep Up with Its Energy Demands?
What’s Your Actual Age? Chronological vs. Biological Age
Natural Ways to Support Your Level of NAD+
Six Ways You Can Benefit From Supplementing with Nicotinamide Riboside (NR)
Intermittent Fasting: Five Tips for Success
Learn more about Dr. Holthouse and his team at Functional Medicine of Idaho
Products mentioned in the episode:
Biological Age Test
Products with Nicotinamide Riboside
Niacel
Advanced Nutrients
Vitamin B Complexes



Subscribe To More Content
Make sure to never miss an episode by subscribing to the show on your podcast app. You can also learn more about what we talked about by visiting Thorne.com and checking out the latest news, videos, and stories on Thorne’s Take 5 Daily blog.
* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.