17 min listen
Diazepam Pharmacology
FromReal Life Pharmacology - Pharmacology Education for Health Care Professionals
Diazepam Pharmacology
FromReal Life Pharmacology - Pharmacology Education for Health Care Professionals
ratings:
Length:
15 minutes
Released:
Feb 27, 2020
Format:
Podcast episode
Description
Diazepam has numerous dosage forms. There are rectal, injectable, and oral formulations of the drug that are commonly used in clinical practice.
Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. I discuss this further in the podcast.
Diazepam is on the Beers list because it has a tendency to accumulate in the geriatric patient population and cause adverse effects like sedation, confusion, and falls.
Respiratory depression, coma, and death are significantly more likely in overdose situations where opioids are used in combination with benzodiazepines like diazepam.
Diazepam has 2 major metabolic pathways. It is broken down primarily by CYP3A4 and CYP2C19, leaving open the potential for numerous drug interactions. I discuss this further in the podcast.
Diazepam is on the Beers list because it has a tendency to accumulate in the geriatric patient population and cause adverse effects like sedation, confusion, and falls.
Respiratory depression, coma, and death are significantly more likely in overdose situations where opioids are used in combination with benzodiazepines like diazepam.
Released:
Feb 27, 2020
Format:
Podcast episode
Titles in the series (100)
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