On this podcast episode, I discuss meperidine pharmacology, adverse effects, pharmacokinetics, drug interactions, and much more!



Meperidine is an opioid that is seldom used due to neurotoxicity. I describe how this can happen in this podcast episode.



Meperidine has numerous drug interactions and using a CYP3A4 inhibitor may increase the risk for toxicity.



Seizures are a risk with meperidine due to its neurotoxic metabolite normeperidine. I discuss this further in this podcast episode.