Pramipexole (Mirapex) is a dopamine agonist that can be used in Parkinson’s disease and Restless Legs Syndrome.



Dopamine agonists like pramipexole can worsen psychiatric symptoms in some patients by causing hallucinations, and obsessive/compulsive symptoms.



Nausea, vomiting, hypotension, and fatigue are the most common adverse effects of pramipexole.



Pramipexole is primarily eliminated through the urine. I discuss how this matters clinically in greater detail in this podcast episode.