I sat down with Louise Agersnap, the Head of WHO Innovation HUB, for a thought-provoking discussion on the transformative initiatives happening at the World Health Organization. With over 20 years of experience in global health development and innovation, Louise brings a wealth of knowledge and insights to the table. The conversation kicks off with a reflection on the global health sector's unique challenges and the critical need for innovative solutions. Recognizing this, WHO is empowering its teams to transition seamlessly from ideation to execution, with a nod to Kevin D'Silva and his team at Ideateplus for their role in fostering a culture of innovation. Louise shares insights into the LEAD program, a groundbreaking initiative at WHO that empowers staff to drive impactful change through ideation, validation, and implementation. With over 250 ideas generated and 40+ projects in the pipeline, the LEAD program exemplifies the power of collaborative innovation in healthcare. The discussion also delves into the role of storytelling in scaling innovation across 194 member states. Louise highlights the Herculean task of communicating and garnering support for innovative ideas globally, offering insights into crafting compelling narratives that inspire collaboration and drive progress. We explore the importance of scalability and sustainability in fostering an innovation culture within WHO. With projects spanning 12 to 18 months, maintaining momentum and ensuring long-term impact are key priorities.