Join us in the third episode of our "Managing Respiratory Distress" series on The Incubator Podcast, featuring Dr. Lonnie Miner and Dr. Amy Miner. Our guests today unravel the intricacies of high-flow nasal cannula and CPAP in the treatment of respiratory distress syndrome (RDS) in neonates. Dr. Lonnie Miner, Assistant Professor in the Division of Neonatology at the University of Utah, School of Medicine, and Dr. Amy Miner, a Neonatology Fellow at Rutgers University, engage in a thorough discussion about the practical differences and physiological impacts of high-flow nasal cannula and CPAP. They emphasize the significance of understanding how much pressure is actually delivered to the neonates, exploring the challenges in measuring this accurately.The conversation covers a range of topics, including the evolution of high-flow nasal cannula, its application in different clinical settings, and the importance of humidification in respiratory support. Our speakers also delve into the nuances of airway resistance and lung compliance, highlighting how these factors influence the effectiveness of respiratory support modalities.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!