In her thirties, Dr. Sara Gottfried’s metabolic function was closer to that of a woman in her fifties. After applying functional medicine principles to herself, within six weeks she had fixed the root cause of her discomfort, reversed her prediabetes, and lost more than 20 pounds. In this episode, Dr. Gottfried and Jeff take a deep dive into metabolism and why metabolic dysfunction is the upstream cause of 9 out of the top 10 killers in the U.S. today. In this episode we cover: 0:06:25 Intro 0:10:07 Metabolism 0:10:48 Metabolic Dysfunction 0:11:56 Measuring Metabolic Health 0:13:24 Continuous Glucose Monitors 0:18:03 Insulin Resistance 0:21:32 Glucose 0:26:34 Symptoms of Improper Glucose Function 0:32:09 Alzheimer's Disease 0:35:55 Unwanted Pharmaceutical Side Effects 0:37:36 Hormones and Cholesterol 0:40:12 Tests to Gauge Metabolic Health 0:48:50 Ketogenic Diet 0:51:53 Microbiome 0:54:26 Testosterone Advantage 0:55:57 Carbs vs Net Carbs 0:57:44 Clean Keto 0:59:07 Saturated Fat 1:00:01 Bioindividuality 1:02:23 Ketosis 1:05:11 Metabolic Crisis in Women 1:05:41 Fasting 1:06:51 Cold Therapy and Hydrotherapy 1:08:02 Hormesis 1:08:45 Human Growth Hormone 1:12:46 Testosterone in Women 1:15:55 Eating Out 1:17:54 Leptin and Ghrelin 1:21:04 Biological Advantages in Women 1:24:14 Trauma 1:31:11 Gut-Brain Axis Learn about Commune and check out all our health, nutrition, and functional medicine courses free for 14 days at onecommune.com/trial. This podcast is suported byInsideTracker: Live healthier longer. InsideTracker is your personalized dashboard. For a limited time, you can get 20% off by visiting insidetracker.com/commune. This podcast is supported by BetterHelp. COMMUNE listeners get 15% off their first month at BetterHelp.com/Commune.