In this episode we welcome Dr. Didem Saygin, a rheumatology fellow from the University of Chicago, to the podcast.  We are also joined by Dr. Guy Katz, a rheumatology fellow from MGH.  We discuss three more topics that would be excellent teams in the upcoming RheumMadness tournament: the newly discovered VEXAS autoinflammatory syndrome, the FAST trial on cardiovascular safety of urate-lowering therapies, and the PEXIVAS trial in ANCA vasculitis. New RheumMadness website! https://sites.duke.edu/rheummadness/References:VEXAS: https://www.nejm.org/doi/full/10.1056/NEJMoa2026834FAST: https://www.thelancet.com/article/S0140-6736(20)32234-0/fulltextPEXIVAS: https://www.nejm.org/doi/full/10.1056/NEJMoa1803537 RheumMadness Music Attribution: Cheery Monday by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/3495-cheery-mondayLicense: http://creativecommons.org/licenses/by/4.0/