Welcome to another episode of Medmastery’s Cardiology Digest! Today, we're diving into three fascinating studies that have stirred up a bit of chatter in the medical world. So grab your coffee and let's delve right in!   First, we dig into a study that issues a wake-up call about the potential accuracy of home blood pressure measurements. A dash of detective work is required here that could be the key to solving the mystery of some blood pressure anomalies. Cue suspenseful music! Picone DS et al. Availability, cost, and consumer ratings of popular nonvalidated vs validated blood pressure–measuring devices sold online in 10 countries. JAMA 2023 May 2; 329:1514. (https://doi.org/10.1001/jama.2023.2661. opens in new tab)   Our second study takes a close look at 24-hour ambulatory blood pressure measurement and its prognostic value. It’s a robust study, but doesn't shy away from addressing some thorny issues surrounding the use of ambulatory monitoring in the U.S. Does this comprehensive blood pressure monitoring lead to better clinical outcomes? This is sure to spark some debate! Staplin N et al. Relationship between clinic and ambulatory blood pressure and mortality: An observational cohort study in 59 124 patients. Lancet 2023 May 5; [e-pub]. (https://doi.org/10.1016/S0140-6736(23)00733-X. opens in new tab)   Lastly, we explore a paper that evaluates whether apixaban, a commonly prescribed oral anticoagulant, had a higher rate of thromboembolic events than warfarin when given to patients with On-X mechanical aortic valves. Tune in as we explore the implications of this eye-opening research!. Wang TY et al. Apixaban or warfarin in patients with an On-X mechanical aortic valve. NEJM Evid 2023 May 6; [e-pub]. (https://doi.org/10.1056/EVIDoa2300067. opens in new tab)   Join us for this informative overview of contemporary research, as we break down complex medical concepts into digestible nuggets of knowledge, suitable for both medical students and healthcare professionals eager to keep up-to-date in cardiology. For show notes, visit us at https://www.medmastery.com/magazine