For the 9th course, Dani and LC do the robot dance with Melodie Christensen (@chemchristensen on Twitter) #MerckChemistry Enabling Technologies group. Melodie shares her unique career path with us, including her current PhD with @procastiprof - more >10 years after starting her career in pharma. Resident expert in reaction automation, robotics and self-optimizing reactions, Melodie shares her journey in high-throughput and data-rich experimentation. We discuss her award winning paper in JOC and how she was able to use some of the insights of this work to develop an autonomously optimized Suzuki reaction! Finally, Melodie schools us on her best smoothie recipes and three letter acronyms.
Read the paper we discussed today here:
Enantioselective Synthesis of α-Methyl-β-cyclopropyldihydrocinnamates - Journal of Organic Chemistry
Data-science driven autonomous process optimization - Communications Chemistry
The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future - OPRD
Automation isn't automatic - Chemical Science
Follow Melodie Christensen - @chemchristensen
Follow the Pharm to Table podcast on Twitter - @PharmtoTablePod
Visit our website at https://anchor.fm/pharm-to-table