Helium shortages can derail research and threaten expensive instruments that depend on the gas to operate safely. In late 2020, analysts predicted—and we reported—that pressures on the global helium market were likely to ease as new production capacity came online. Today, helium users are again facing price spikes and limited supplies, driven by a variety of factors including political instability in Europe and technical malfunctions at key suppliers. In this bonus episode of Stereo Chemistry, C&EN industrial gas reporter Craig Bettenhausen explains how we ended up here again and how the outlook for the global helium market has evolved. A transcript of this episode is available at bit.ly/3tBSGzF. For more background about where helium comes from, why it's so important to science, and what happens when you can't get enough of it, check out our October 2020 podcast episode, How helium shortages have changed science. Image credit: Boris Steinberg, Johns Hopkins Chemistry Music credit:  “How Did I Get Here” by Sean Solo Contact Stereo Chemistry by emailing cenfeedback@acs.org.