This episode is a lively dialogue for easy listening – with anecdotes and laughter mixed in. We delve into the unique relationship of saving natural teeth and considerations when endodontic treatment planning must bring in single or multiunit implant-supported prosthesis as viable replacement options. We tie in the results of multiple systematic reviews indicating high survival rates for both the natural tooth and for the restored single‐tooth implant. Episodes of Endo Voices may include opinion, speculation and other statements not verifiable in the scientific method and do not necessarily reflect the views of AAE or the sponsor(s). Listeners should use their best judgment in evaluating the merits of any content. To learn more about the American Association of Endodontists, visit aae.org.