84 min listen
69. What’s to blame for Insulin Resistance, Carbs or PUFAs? A very friendly debate with Ben Bikman, PhD
69. What’s to blame for Insulin Resistance, Carbs or PUFAs? A very friendly debate with Ben Bikman, PhD
ratings:
Length:
135 minutes
Released:
Sep 8, 2020
Format:
Podcast episode
Description
Benjamin Bikman earned his PhD in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore studying metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the origins and consequences of metabolic disorders, including obesity and diabetes, with a particular emphasis on the role of insulin. He frequently publishes his research in peer-reviewed journals and presents at international science and public meetings. Time Stamps 0:11:14 Podcast Begins 0:11:54 Ben's Background 0:17:53 The root of chronic disease 0:25:38 All about insulin 0:31:14 Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification https://www.semanticscholar.org/paper/Regulation-of-free-fatty-acid-metabolism-by-insulin-Campbell-Carlson/9be324b8af9ced5a8b7e1902257e3fb9308b4db1 0:31:51 Insulin stops lipolisis 0:34:35 Insulin's affect on the liver 0:40:10 Insulin and muscle cells 0:43:20 Why you want to increase protein as you age 0:48:47 Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988204/#:~:text=Low%20Protein%20Intake%20is%20Associated,Younger%20but%20Not%20Older%20Population&text=Cell%20Metab.,Author%20manuscript. 0:51:00 Animal-based diets optimize muscle protein sythesis 0:55:12 Industrial Seed oils have a fantastic publicist 0:58:05 Do carbs drive metabolic dysfunction? 1:07:07 Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man https://link.springer.com/article/10.1007/BF00400466 1:07:42 How linoleic acid drives metabolic dysfunction 1:09:32 How linoleic acid drives metabolic dysfunction. 1:11:47 Low serum insulin in traditional Pacific Islanders--the Kitava Study https://www.metabolismjournal.com/article/S0026-0495(99)90258-5/pdf 1:14:29 Carbs are not to blame 1:19:05 Thriving is dependent on micronutrients 1:22:19 The secret to overcoming plateaus on low carb diets 1:25:28 Epidemiological studies in a total highland population, Tukisenta, New Guinea: Cardiovascular disease and relevant clinical, electrocardiographic, radiological and biochemical findings https://www.sciencedirect.com/science/article/abs/pii/0021968173900313 1:25:58 Classification of Obesity with Respect to Morbidity https://journals.sagepub.com/doi/abs/10.3181/00379727-200-43417?journalCode=ebma 1:27:46 Does fructose make us fat? 1:28:32 What makes honey different? 1:30:45 Effect of honey in preventing gingivitis and dental caries in patients undergoing orthodontic treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095052/#:~:text=Within%20the%20limitations%20of%20the,in%20patients%20undergoing%20orthodontic%20treatment. 1:31:11 Substituting Honey for Refined Carbohydrates Protects Rats from Hypertriglyceridemic and Prooxidative Effects of Fructose https://academic.oup.com/jn/article/132/11/3379/4687329 1:32:15 Effect of fructose on body weight in controlled feeding trials https://www.ncbi.nlm.nih.gov/books/NBK84702/ 1:33:21 Oral health in transition: the Hadza foragers of Tanzania https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172197 1:34:53 Hyperplastic vs hypertrophic fat cell growth 1:40:01 FADH2, NADH, and mitochondrial magic 1:43:27 Diet fat composition alters membrane phospholipid composition, insulin binding, and glucose metabolism in adipocytes from control and diabetic animals https://www.jbc.org/content/265/19/11143 1:43:27 Unwanted insulin sensitivity 1:50:01 Dietary Stearic Acid Leads to a Reduction of Visceral Adipose Tissue in Athymic Nude Mice https://www.researchgate.net/publication/265650090_Dietary_Stearic_Acid_Leads_to_a_Reduction_of_Visceral_Adipose_Tissue_in_Athymic_Nude_Mice 1:52:16 dietary stearic acid regulates mitochondria in vivo in humans https://www.nature.com
Released:
Sep 8, 2020
Format:
Podcast episode
Titles in the series (100)
Man boobs, low T and breast cancer due to excess estrogens! A scary conversation with Dr. Anthony Jay: Xenoestrogens, phytoestrogens, mycoestrogens, they are everywhere and they are causing testosterone levels to decline in men and breast cancer rates to rise in women. They are also doing all sorts of other bad things to mess up our hormones. You’ll... by Paul Saladino MD podcast