Ryan Cooper used his computer to try and predict time trial splits during the 2013 Tour de France.  His first go at it produced some very accurate results.  That project turned into a business at BestBikeSplit.com.

Cyclists using a power meter can use their power meter to help predict and guide race performance.  This is cutting edge stuff that continues to evolve.  If you race with a power meter this software should help you improve your performance.