Everyday Pharmacology: How Drugs Affect Your Body and Mind
By Arthur Wang
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About this ebook
Dive into the fascinating world of pharmacology with this comprehensive guide, offering insights into the mechanisms, effects, and applications of medications. From everyday drugs to complex treatments, explore how pharmacology impacts health, wellness, and everyday life. Whether you're a healthcare professional seeking deeper knowledge or an individual curious about medications, this book empowers you to make informed decisions for yourself and your loved ones.
Wellness Demystified: A Comprehensive Medications Guide
Explore a holistic approach to well-being with our inclusive medication resource. Dive into an extensive list of medications for the 30 most common illnesses, empowering you to make informed decisions about your health.
Discover the intricate world of pharmacology as we delve into common drug classes and herbal remedies, integrating principles from traditional Chinese medicine (TCM) for a comprehensive understanding.
Stay abreast of the latest medical breakthroughs and medications, ensuring you have access to cutting-edge information to support your health journey. Our illustrations vividly depict drug mechanisms and actions, demystifying complex concepts for all readers.
Whether you're a healthcare professional seeking to deepen your knowledge or a curious individual looking to enhance your understanding of medications, our easy-to-follow guide is tailored to meet your needs. Empower yourself with the knowledge to make informed decisions about your health and well-being, as well as that of your loved ones
Features
- Explore a comprehensive list of medications for the 30 most common illnesses.
- Stay up-to-date with the latest medical breakthroughs and medications.
- Visualize drug mechanisms and actions through illustrative depictions.
- Access an easy-to-understand medication guide tailored for the general public.
- Gain insight into common drug classes and herbal remedies, incorporating principles from Traditional Chinese Medicine (TCM).
Arthur Wang
Arthur Wang is an enthusiastic writer on various topics on the internet. He had extensive studies in biochemistry, microbiology, immunology, western medicine and traditional Chinese medicine. He graduated from UCLA.
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Everyday Pharmacology - Arthur Wang
Introduction
Obtaining prescription drugs post-visit to a doctor has become routine for many nowadays, as it’s ingrained in the belief that medication effectively resolves medical issues. However, some individuals may be driven by psychological factors to seek prescriptions, even when unnecessary. On the other hand, some strongly resist medication, citing worries about side effects or a preference for exploring alternative options.
To optimize the benefits and minimize potential side effects of medication, it’s imperative to deepen our understanding of how drugs interact with our bodies. While numerous drugs may address similar conditions, one may be more suitable than another for a particular individual.
The field of pharmacology, exploring how drugs affect the body, may appear daunting to laypersons. This book aims to demystify pharmacology for everyday readers, presenting complex concepts in a clear and accessible manner. Enhanced comprehension of drug interactions empowers individuals to advocate for themselves effectively and facilitates better communication with healthcare providers. Moreover, it might reveal other medication choices beyond the ones first recommended. However, it’s crucial to underscore that the information provided in this book should not substitute consultation with a qualified medical professional. Always seek guidance from a healthcare provider before making any decisions regarding medication.
1
Chapter 1: Quick Understanding on Pharmacology
Welcome to Quick Understanding on Pharmacology.
In this section, I’ll simplify complex drug concepts, making pharmacology accessible to all. By the time you’ve finished a third of the book, you’ll be amazed at how easy it is to grasp. Stick to the sequential reading for maximum benefit and use this section as your go-to reference in the future. Let’s dive in!
How a drug is born?
Substances utilized for treating illnesses are commonly referred to as drugs. As new applications for existing drugs are discovered or new drugs are developed, the list of available medications undergoes periodic updates. In the United States, the average time it takes for a new drug to receive approval from the FDA is approximately 10 to 12 years. This process can be broken down into several stages, including pre-clinical testing and three phases of clinical trials. The FDA aims to review and act on at least 90% of New Drug Applications (NDAs) for standard drugs no later than 10 months after the applications are received. The review goal is six months for priority drugs.
As for the cost, developing a new drug is a costly endeavor. The cost of bringing a new drug to market, from drug discovery through clinical trials to approval, typically ranges from hundreds of millions to billions of U.S. dollars. In an analysis of the drug development costs for 98 companies over a decade, the average cost per drug developed and approved by a single-drug company was $350 million. For companies that approved between eight and 13 drugs over 10 years, the cost per drug went as high as $5.5 billion. However, these figures can vary widely depending on the complexity of the drug and the length of the development process. Additionally, post-approval trials, which are sometimes mandated by the FDA as a condition of approval, are conducted; these are known as Phase 4 Trials or Post-Marketing Surveillance Trials.
The Process of New Drug Development
Drug Discovery
Synthesis, Development & Screening: 2-10 years
Pre-Clinical Testing
Lab and Animal Testing: 3-5 years
(Phase I ~ Phase III: 3 -5 year)
Phase I
Determine safety and dosage
Phase II
Assess efficacy and side effects
Phase III
Monitor efficacy and adverse reactions to long-term use
NDA (New Drug Application) Filling: 1-3 years
FDA Review and Approval
Phase IV
Post-marketing Studies and product surveillance: 4-10 years
The journey of a drug from conception to arrival on pharmacy shelves is a complex and lengthy process involving multiple steps and rigorous testing. In recent years, the landscape of drug discovery has been revolutionized by the integration of artificial intelligence (AI) technology. Through sophisticated algorithms and machine learning techniques, AI has accelerated the process of identifying potential drug candidates and predicting their efficacy with unprecedented speed and accuracy. By analyzing vast datasets of biological and chemical information, AI algorithms can identify patterns and relationships that traditional methods might overlook, leading to the discovery of novel medications and treatments for a wide range of diseases. This symbiotic relationship between AI and drug discovery holds promise for faster, more efficient development of life-saving medications, ushering in a new era of innovation in healthcare.
Potency and Efficacy
A drug’s effects can be assessed based on its strength (potency) or effectiveness (efficacy). Potency refers to the quantity of drug (typically measured in milligrams) required to elicit a specific effect, such as pain relief or blood pressure reduction. For example, if 5 milligrams of drug A alleviates pain to the same degree as 10 milligrams of drug B, then drug A is considered twice as potent as drug B.
Potency and efficacy are two important concepts to understand when it comes to pharmacology and how drugs affect the body and mind. Potency refers to the strength of a drug, or how much of a drug is needed to produce a specific effect. A drug with high potency will produce a desired effect at a lower dose than a drug with low potency. This is important to consider when taking medications, as a drug that is too potent can have harmful side effects.
On the other hand, efficacy refers to the ability of a drug to produce a desired effect. A drug with high efficacy will produce a strong effect, even at low doses. Understanding the efficacy of a drug is crucial for health- conscious individuals, nurses, patients, and alternative medicine practitioners, as it can help determine the most effective treatment for a particular condition.
When it comes to choosing a medication, it’s important to consider both potency and efficacy. A drug with high potency but low efficacy may not be the best choice, as it may require higher doses to achieve the desired effect. Conversely, a drug with high efficacy but low potency may be more effective at lower doses, reducing the risk of side effects.
In everyday pharmacology, understanding the concepts of potency and efficacy can help individuals make informed decisions about their health and well-being. By working closely with healthcare providers and pharmacists, patients can ensure they are receiving the most effective treatment for their specific needs. Additionally, alternative medicine practitioners can use this knowledge to provide safe and effective treatments to their clients. Overall, a solid understanding of potency and efficacy is essential for anyone interested in how drugs affect the body and mind.
Four Major Effects of Drug
In the world of pharmacology, it is important to understand the various effects that drugs can have on the body and mind. There are four major effects of drugs that everyone should be aware of, whether you are a health-conscious individual, nurse, patient, alternative