Mesothelioma Cancer: 10 treatment options: Mesothelioma is a form of Cancer that is becoming more and more common...

By Karllo MELLO

Mesothelioma is a form of cancer that is becoming more and more common. The most common cause of this cancer is exposure to asbestos. When constantly exposed within sufficient protection, asbestos dust and fibres affect the mesothelial cells which make up the mesothelium. Treatment of recurrent malignant mesothelioma may be one of the following:Surgery to remove part of the chest wall.Chemotherapy, if it was not given as initial treatment.A clinical trial of immunotherapy.A clinical trial of targeted therapy.A clinical trial of chemotherapy.A clinical trial of surgery.

• Language: English
• Publisher: Bibliomundi
• Release date: Aug 31, 2022
• ISBN: 9781526032515

Book preview

Mesothelioma Cancer an Overview

M e s o t h e l i o m a T r e a t m e n

10 options

By Karlo Mello - Researcher

1. Mesothelioma the largest man made epidemic

Mesothelioma – The largest man made epidemic with the teacher lorraine kember.

It is documented that Australia had the highest per capita use of asbestos in the world from the 1950’s until the 1970’s. As a tragic consequence, Australia now has the highest per capita incidence of mesothelioma in the world. With more than 500 Australians contracting mesothelioma per year, it is estimated that up to 18,000 Australians will die from this asbestos related cancer by the year 2020.

Despite the growing awareness of the dangers of asbestos, there are many people who have not heard of Mesothelioma. This asbestos related cancer is defined as a malignant spreading tumor of the mesothelium of the pleura, pericardium, or peritoneum, arising form the inhalation of asbestos fibers.

One of the most baffling and frightening known facts concerning Mesothelioma is that many years may pass, between inhalation of asbestos dust and its deadly legacy of disease; it is not uncommon for four decades or more to pass before symptoms due to asbestos dust inhalation become apparent.

In November 2004, I was an invited speaker at the Global Asbestos Congress 2004, held in Tokyo Japan. Over 800 participants from 40 countries around the world were in attendance. To be a part of such a large gathering of fellow humans, united in a quest to rid the poison of asbestos from our environments was an intensely moving experience. Having lost my husband to mesothelioma I know firsthand the suffering this cruel disease places on its innocent victims.

There were many speakers, and each told a tale, of pain, death and heartache. We listened, we understood, and we ached for the past, present and future victims of the killer asbestos and its legacy of mesothelioma and other asbestos related diseases. We listened and we were shocked and angered to learn that despite the growing awareness of the dangers of asbestos and the increasing incidence of asbestos related disease, there remains some countries who are mining asbestos with little or no regard for their workers or people who will come into contact with asbestos products.

Asbestos disease Association member’s worldwide are working tirelessly and fighting almost insurmountable odds to ban asbestos from all countries of the world. It is a sobering and frightening fact, that even if we were successful in this quest, the legacy of asbestos related diseases will continue for five decades.

The Asbestos Disease Awareness Organization (ADAO) continues to raise public awareness about the dangers of asbestos exposure and the incurable and often deadly asbestos related diseases. ADAO is quickly expanding and uniting veterans, fire-fighters, shipbuilders, teachers and thousands of other innocent people around the world. Asbestos Awareness leads to education, prevention, new treatments and ultimately a cure.

2. Mesothelioma your basic information

Mesothelioma is a form of cancer that is becoming more and more common. The most common cause of this cancer is exposure to asbestos. When constantly exposed within sufficient protection, asbestos dust and fibres affect the mesothelial cells which make up the mesothelium. The mesothelium is the outer lining that protects some of the body’s most vital organs such as the heart and lungs. The mesothelial cells become abnormal after lengthy periods of constant exposure to asbestos causing an array of problems.

Due to the latency period and symptoms of this cancer, mesothelioma is very difficult to diagnose. Mesothelioma takes decades to mature and develop fully and this is why many elderly men who were exposed to asbestos thirty years before are just discovering they have the cancer. A lot of these men are currently lodging multi-million-dollar lawsuits against the companies that exposed them to the dangers of asbestos without sufficient protection.

The organs that are affected most by mesothelioma are the lungs. The most common type of mesothelioma which is called pleural mesothelioma affects the lining of the lungs and can cause symptoms such as coughing, breathing and swallowing difficulties, shortness of breath and fever. Another area that can be affected by mesothelioma is the abdomen. This is less common, and this is known as peritoneal mesothelioma. Symptoms of peritoneal mesothelioma include nausea and vomiting, weight loss, fever, bowel obstruction, loss of appetite and general pain in the stomach area. The last and least common type of mesothelioma is known as pericardial mesothelioma and it affects the heart and the tissue surrounding it. Symptoms of this form of the cancer include palpitations, breathing difficulties and persistent coughing. Generally, the symptoms of mesothelioma are typical of many other diseases and this makes it very difficult to diagnose.

3. Malignant mesothelioma the cancer of the mesothelial cells

The diseased defined

Mesothelium is the protective tissue that covers the chest cavity, abdominal cavity and the cavity around the heart and also produces a special lubricating fluid that allows the internal organs of the body to move around. Malignant Mesothelioma can be defined as the cancer of the mesothelial cells which become abnormal and start dividing without any order. Majority of the mesothelioma patients have a prior history of exposure to asbestos.

Types of malignant Mesothelioma

Malignant Mesothelioma or simply Mesothelioma can be divided into 3 main types namely

– Epithelioid

– Sarcomatoid

– Mixed/biphasic

Of these, Epithelioid is the most common (50% to 70% cases) and stands the best chance of recovery. Sarcomatoid type is seen in 7% to 20% cases whereas mixed/biphasic type is seen in

20% to 35% cases.

4. Mesothelioma cancer an overview

The cause of mesothelioma cancer:

Mesothelioma is a cancer caused by exposure to asbestos without sufficient protection overtone’s mouth and nose. Asbestos is a fibrous mineral which was discovered in the 1860s but not properly used until the 1930s. Asbestos was used hugely in construction due to its property of being fireproof even at high temperatures. It was not until the 1960s that it became clear that asbestos was causing a number of diseases. These diseases include mesothelioma, asbestosis and lung cancer.

Asbestos as the cause of mesothelioma:

When exposed to asbestos without sufficient protection, a person will inhale many tiny asbestos fibres that are suspended in the air. These will pass into the respiratory system and get most probably get lodged in the lining of the lungs. An accumulation of these fibres can cause the cells around it to become abnormal and this can lead to mesothelioma. Through the lymphatic system, asbestos fibres can become lodged in the lining of the abdomen or in the lining of the heart.

The suffering endured by patients of mesothelioma:

The symptoms of mesothelioma vary depending on what type of mesothelioma a patient has. However, there are several common symptoms of all types.

These include chest pain, shortness of breath, coughing, coughing up blood, weight loss and loss of appetite. These symptoms usually take affect only when the mesothelioma cancer has fully matured and developed. Due to the fact that these symptoms are frequent for a number of more common diseases such as pneumonia, mesothelioma is very difficult to diagnose in its early stages.

The treatments available for mesothelioma:

As yet, all treatments for mesothelioma have a low success rate. The effectiveness of treatment depends largely on how aggressively and early the cancer is treated. If treated in its later stages when it has fully developed, it is extremely difficult, almost impossible to cure.

Treatments include surgery which comes in two forms, aggressive surgery and palliative procedures, radiation therapy, chemotherapy and dual therapy which is a combination of all three main treatments combined. Dual therapy has shown the most promising signs so far as a cure for mesothelioma.

Mesothelioma research:

Research is being undertaken in numerous research labs all across the United States although so far, no breakthroughs have been made. Many pharmaceutical companies are also endeavoring to find new drugs for chemotherapy. Researchers have recently predicted that a

long awaited new treatment method for mesothelioma is on the way to being