The Atlantic

We Still Don’t Know What Fundamentally Causes Canker Sores

But it’s probably the immune system’s fault.
Source: Erik Carter/The Atlantic; Getty

A canker sore—a painful white ulcer inside the mouth—might be brought on by stress. Or the wrong toothpaste. Or certain foods: tomatoes, peanuts, cinnamon. Or an iron deficiency. Or an allergy. Or a new prescription. Or an underlying autoimmune disease.

Even though millions of people suffer from them every year, researchers still don’t know much about what fundamentally causes these sores. This leaves doctors and dentists stuck playing detective with their patients—running down a checklist, trying to figure out which of more than a dozen potential triggers could’ve set off the

You’re reading a preview, subscribe to read more.

More from The Atlantic

The Atlantic4 min read
Hayao Miyazaki’s Anti-war Fantasia
Once, in a windowless conference room, I got into an argument with a minor Japanese-government official about Hayao Miyazaki. This was in 2017, three years after the director had announced his latest retirement from filmmaking. His final project was
The Atlantic5 min read
The Strangest Job in the World
This is an edition of the Books Briefing, our editors’ weekly guide to the best in books. Sign up for it here. The role of first lady couldn’t be stranger. You attain the position almost by accident, simply by virtue of being married to the president
The Atlantic2 min read
Preface
Illustrations by Miki Lowe For much of his career, the poet W. H. Auden was known for writing fiercely political work. He critiqued capitalism, warned of fascism, and documented hunger, protest, war. He was deeply influenced by Marxism. And he was hu

Related Books & Audiobooks