NPR

Coronavirus FAQ: I'm immunocompromised. Will pills, gargles and sprays fend off COVID?

People who are immunocompromised continue to worry about COVID. A raft of products promise protection. Is there any evidence they can protect from infection or lessen severity of disease?
Source: Marc Silver/NPR

We regularly answer frequently asked questions about the coronavirus. If you have a question you'd like us to consider for a future post, email us at goatsandsoda@npr.org with the subject line: "Weekly Coronavirus Questions." See an archive of our FAQs here.

My husband is immuno-compromised. He scours the internet for products that can protect him against COVID – from mouthwashes to supplements. Is there any evidence that any of these products work?

Four years into the COVID pandemic,many people are relaxing their precautions. But it's still tough to be immunocompromised, perhaps even tougher than a year or two ago.

Back then, an immunocompromised person who caught COVID could get monoclonal antibody treatments, which were effective at lessening the severity of the disease and could even help prevent infection if taken prophylactically. But those treatments are now all gone. The Food and Drug Administration pulled them from the market as the virus evolved, rendering them ineffective.

Yes, we still have vaccines and effective antiviral treatments like paxlovid. But for some immunocompromised folks, vaccines are often less effective as their weakened immune systems fail to mount a sufficient response,and paxlovid can interfere with many commonly prescribed medications. Well-fitted, work well, but

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