NPR

Coronavirus FAQ: I took Paxlovid. I felt better. Then symptoms rebounded. What's up?

The antiviral drug is prescribed to those at risk of severe disease. It's been credited with reducing hospitalizations. But then there's the "Paxlovid rebound."
Source: Justin Paget

We regularly answer frequently asked questions about life during the coronavirus crisis. If you have a question you'd like us to consider for a future post, email us at goatsandsoda@npr.org with the subject line: "Weekly Coronavirus Questions." See an archive of our FAQs here.

I took the anti-COVID drug Paxlovid, my symptoms diminished — and then they returned. Is this common? Worrisome?

That's the so-called "Paxlovid rebound." And here's a first-person testimonial from NPR science correspondent Joe Palca, who's a rebounder.

"I started having COVID symptoms on Saturday, May 6. Persistent cough. On Sunday symptoms got much worse. That day I had a negative rapid test. I also dropped

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