Arizona Cardinals, sitting at 4-6 with their season still in the balance, have an incredibly important inter-divisional matchup on Monday night in Mexico City against the San Francisco 49ers. With Kyler Murray still hobbled, it looks like it'll be Colt McCoy leading the offensive charge to potentially go 2-0 in his last two starts against the 49ers. Hollywood Brown could be back, and it's so important for the offense to be fluid and effective like they were last week against the Los Angeles Rams. Can the Cardinals defense stop Christian McCaffrey, Deebo Samuel, George Kittle, and the rest of the 49ers offense? The Arizona Cardinals need to do three things if they want to beat the San Francisco 49ers on Monday Night Football in Mexico City.BetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts!Find and follow Locked On Cardinals on your favorite podcast platforms:Apple https://apple.co/3gzT6PgSpotify https://spoti.fi/3wsOL7aAudacy https://bit.ly/3xdaqjUStitcher https://bit.ly/3cFWffnGoogle https://buff.ly/2yH7WOlMegaphone https://bit.ly/2RUBlC5 Learn more about your ad choices. Visit podcastchoices.com/adchoices