Arizona Cardinals find themself in another must-win battle against an NFC West rival. This time, it's the San Francisco 49ers in Mexico City. What looks to be Colt McCoy's second start in a row in place of Kyler Murray who continues to nurse his hamstring, this time it'll potentially be witnessing the first time both Hollywood Brown and DeAndre Hopkins on the field at the same time wearing an Arizona Cardinals uniform. Can the banged up offensive line protect Colt McCoy well enough or will the pass rush of the San Francisco 49ers have their way? Brian Peacock and Eric Crocker of Locked On 49ers join Alex Clancy for a Crossover Thursday.Make your moment sparkle with Blue Nile. Go to BlueNile.com and use code lockedon to save fifty dollars on your purchase of five-hundred dollars or more.BetOnline.net has you covered this season with more props, odds and lines than ever before. BetOnline – Where The Game Starts! Learn more about your ad choices. Visit podcastchoices.com/adchoices