Got a minute to ponder the fleeting beauty of life and the tantalizing possibility of extending our time here? Come on a journey with us, as we reflect on gratitude, transience, and the magic of potential longevity drugs. In our year-end episode, we're revisiting one of our most engaging topics from the past year - the promising molecules of Rapamycin and Metformin. Have you ever wondered what would happen if we could use modern medicine to extend our lives? We're taking a deep look at two fascinating drugs that might just make this sci-fi concept a reality. We'll walk you through the ins and outs of these potential longevity gems, discussing their mechanism of action, available evidence of their lifespan lengthening effects, their rich histories, and important safety considerations. You'll get a glimpse of the intriguing study that sparked interest in Metformin's potential for longevity and the ongoing debates surrounding these potential life-extending drugs.But we're not stopping there. We'll guide you through an exploration of Metformin, commonly used for type 2 diabetes, and its potential to reduce all-cause mortality, cancer, cardiovascular disease, and neurodegeneration. Rapamycin also gets its fair share of the spotlight, revealing promising anti-aging effects in animal studies and potential benefits for diseases of aging. As we cap off another year, join us in appreciating the present moment, expressing gratitude for each day, and contemplating the exciting possibilities that the future of longevity research holds.*** CONNECT WITH ROB ON SOCIAL MEDIA ( ~250k)*** Web: https://robertlufkinmd.com/X(Twitter): https://twitter.com/robertlufkinmdYoutube: https://www.youtube.com/RobertLufkinMDInstagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/Threads: https://www.threads.net/@robertlufkinmd *** SPONSORSHIPS & BRANDS ***We do work with sponsors and brands. If you are interested in working with us for your health industry product or service, please contact us at: https://www.robertlufkinmd.com/contact/ NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here.