In this installment, 2023 ASH Summit on Immunotherapies for Hematologic Diseases co-chair Dr. Terry Fry, and The Hematologist Editor-in-Chief Dr. Shaji Kumar have a conversation about what attendees can expect for this year’s summit, taking place in-person only. They discuss the current progress of immunotherapies for treating hematologic malignancies, some of the limitations to bringing these kinds of therapies to patients, manufacturing and regulatory issues, management of toxicities, and more, all to be specifically addressed during the summit. Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/