The Case:  Melissa is 40 and has been dealing with brain fog for over 5 years. Everything seemed fuzzy, she forgot words or where she’d put things. She tried working with her conventional doctor, but got nowhere.    The Investigation When she came to see me, I noted that she was also experiencing periods of stress, trouble sleeping, feeling down, fatigue, and even weight gain. I suspected that her brain fog was related to these other symptoms.    Dr. Rodger Murphree sees many patients dealing with brain fog and knows that there can be many different underlying causes. Often, his patients come in and explain away the brain fog as ‘just getting older’ or joking about having ‘a senior moment’. This is frustrating because often, that is not the case and this loss of mental clarity is treatable, if you can get to the root cause.    6 Common Causes (and Treatments) of Brain Fog   Deficient Neurotransmitters    One of the most common denominators in brain fog cases is low serotonin. Serotonin is a brain chemical often referred to as the ‘happy hormone’ because of the role it plays in healthy moods, calming hormones, reducing plain, and regulating bowel movements. Norepinephrine is another neurotransmitter that can be out of balance and cause challenges with mental clarity.       Sleep   Issues with serotonin can also cause sleep cycle issues, and this can exacerbate the brain fog problem. Sleep is essential for mental clarity because it impacts those brain chemicals. Deep restorative sleep is required to replenish stress coping chemicals, like serotonin and for the mental clarity to return.    Stress & Adrenal Fatigue   Low cortisol caused by chronic stress can put the body into adrenal fatigue. One of the common symptoms of this depleted adrenal state is brain fog.    Proton Pump Inhibitors and other drugs.   Many people take proton pump inhibitors (like Nexium and Prilosec) or histamine antagonists like Zantac to treat GERD, acid reflux or other gastrointestinal issues. These drugs block stomach acid but that interferes with the body’s ability to absorb and make B12 and B1 (thiamine) both of which are key nutrients needed for thought clarity.    Thyroid   Brain fog is a common symptom of hypothyroidism however, it is often overlooked especially if traditional (surface level) lab tests don’t reveal that the thyroid is not performing optimally.    Food Sensitivities   The gut/brain connection is well documented which is why food is one of the first places to look in solving a brain fog mystery. The issue could be caused by a specific food sensitivity or an issue with the gut microbiome.  Treating Brain Fog The key to treating brain fog is to determine what the cause of it is. If it is a neurotransmitter issue like low serotonin or norepinephrine, then there are supplements that can help to restore levels but getting enough deep, restorative sleep also has to be a part of the strategy. Sufficient sleep is also required to reset the adrenals and reduce stress-induced brain fog. Dr. Murphree also suggests supplementing with DHEA, Gaba(gamma-aminobutyric  acid) L-Theanine, Ashwagandha or valerian root depending on the patient.   If stress or adrenal fatigue is the cause of the brain fog, supporting the adrenal glands so they can improve cortisol production is key (as is reducing stress to avoid it happening again). Dr. Murphree explains in this episode why it’s so important to get the right kind of adrenal support supplement - namely the Adrenal Cortex Only Glandular.  When the brain fog is a result of prescription drug use, the solution is to find a natural treatment (and in many cases to find the root cause instead of masking the symptoms with medication).    If the thyroid is the cause of the brain fog - especially if it is a subclinical case of hypothyroidism, then optimizing the thyroid is the way to regain mental clarity.    Determining food sensitivities requires doing either an elimination diet and/or lab tests. O