Chlamydia infection can be treated with either azithromycin or doxycycline. Increasing evidence supports the use of doxycycline over azithromycin for the treatment of rectal chlamydia infection. This podcast summarizes literature on this topic. View episode transcript and references at www.std.uw.edu.Editor and host Dr. Meena Ramchandani is an Assistant Professor of Medicine at the University of Washington (UW) and Medical Director of the Public Health – Seattle & King County Sexual Health Clinic. This podcast is dedicated to an STD [sexually transmitted disease] literature review for health care professionals who are interested in remaining up-to-date on the diagnosis, management, and prevention of STDs.