9 min listen
Morphine Pharmacology
FromReal Life Pharmacology - Pharmacology Education for Health Care Professionals
Morphine Pharmacology
FromReal Life Pharmacology - Pharmacology Education for Health Care Professionals
ratings:
Length:
14 minutes
Released:
Nov 7, 2019
Format:
Podcast episode
Description
Morphine has opioid agonist activity that can cause respiratory depression and death in overdose.
Morphine-6-glucuronide is the metabolite that can accumulate and cause CNS toxicity in renal failure.
Be aware of CNS depressants that may enhance the effect of morphine and other opioids. Some examples of CNS depressants include gabapentin, benzodiazepines, older antihistamine, skeletal muscle relaxants, and pregabalin.
Opioid withdrawal is a significant concern when patients have their morphine or another opioid abruptly stopped. Some signs of withdrawal include agitation, mood swings, anxiety, sweating, GI upset, pain, and insomnia.
Morphine-6-glucuronide is the metabolite that can accumulate and cause CNS toxicity in renal failure.
Be aware of CNS depressants that may enhance the effect of morphine and other opioids. Some examples of CNS depressants include gabapentin, benzodiazepines, older antihistamine, skeletal muscle relaxants, and pregabalin.
Opioid withdrawal is a significant concern when patients have their morphine or another opioid abruptly stopped. Some signs of withdrawal include agitation, mood swings, anxiety, sweating, GI upset, pain, and insomnia.
Released:
Nov 7, 2019
Format:
Podcast episode
Titles in the series (100)
Aminoglycoside Pharmacology Episode 006: On this episode, I will discuss aminoglycoside pharmacology. Gentamicin and tobramycin are the two classic examples of aminoglycosides. We will review how these medication work in the body, adverse effects, by Real Life Pharmacology - Pharmacology Education for Health Care Professionals